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Find clinical trials for Pancreatic Cancer in Pittsburgh, PA

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Pittsburgh, PA, USA:

Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to prior treatment of metastatic pancreatic...

Enrolling
Metastatic Pancreatic Cancer
Drug: Azeliragon

Phase 1, Phase 2

Cantex Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 5 other locations

and clinical activity of AB680 in combination with Zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...

Enrolling
Advanced Pancreatic Cancer
Drug: Gemcitabine
Drug: Zimberelimab

Phase 1

Arcus Biosciences
Arcus Biosciences

Pittsburgh, Pennsylvania, United States and 17 other locations

A Phase Ib/II, open-label, multicenter, randomized study designed to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumor...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Gemcitabine
Drug: Bevacizumab

Phase 1, Phase 2

Roche
Roche

Pittsburgh, Pennsylvania, United States and 26 other locations

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...

Enrolling
Locally Advanced Pancreatic Cancer
Device: RenovoCath
Drug: nab-paclitaxel

Phase 3

RenovoRx

Pittsburgh, Pennsylvania, United States and 38 other locations

This trial will study tisotumab vedotin to find out whether it is an effective treatment alone or with other anticancer drugs for certain solid tumors...

Enrolling
Exocrine Pancreatic Cancer
Colorectal Neoplasms
Drug: cisplatin
Drug: carboplatin

Phase 2

Seagen
Seagen

Pittsburgh, Pennsylvania, United States and 71 other locations

and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...

Active, not recruiting
Neoplasm of Lung
Neoplasms Pancreatic
Drug: Gemcitabine - 21 day cycle
Drug: 9-ING-41

Phase 2

Actuate Therapeutics

Pittsburgh, Pennsylvania, United States and 65 other locations

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...

Active, not recruiting
Breast Cancer
Colon Cancer
Biological: E-602
Biological: Cemiplimab

Phase 1, Phase 2

Palleon Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 12 other locations

administered orally as monotherapy in patients with advanced solid tumors with gene alterations in the RAS- MAPK pathway for whom there are ...

Enrolling
Solid Tumor, Adult
Pancreatic Cancer
Drug: IK-595

Phase 1

Ikena Oncology

Pittsburgh, Pennsylvania, United States and 4 other locations

of care. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic...

Active, not recruiting
Advanced Cancer
Gastric Cancer
Drug: mFOLFOX6
Drug: Gemcitabine

Phase 1, Phase 2

Transcenta

Pittsburgh, Pennsylvania, United States and 17 other locations

targets both EGFR with TGFβ. Based on preclinical data, this bifunctional antibody may exert synergistic activity in patients with EGFR-driven tumors...

Enrolling
Epithelial Ovarian Cancer
Pancreas Cancer
Drug: BCA101
Drug: Pembrolizumab

Phase 1

Bicara Therapeutics
Bicara Therapeutics

Pittsburgh, Pennsylvania, United States and 18 other locations

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