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Find clinical trials for Pancreatic Cancer in Pittsburgh, PA

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Related conditions:

Adenocarcinoma
Cancer
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Carcinoma
Lung Cancer
Ovarian Cancer

Pancreatic Cancer trials near Pittsburgh, PA, USA:

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer (ENACT)

is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic...

Enrolling
Locally Advanced Pancreatic Adenocarcinoma
Drug: Modified FOLFIRINOX
Combination Product: Acoustic Cluster Therapy

Phase 2

EXACT Therapeutics

Pittsburgh, Pennsylvania, United States and 3 other locations

to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to prior treatment of metastatic pancreatic...

Enrolling
Metastatic Pancreatic Cancer
Drug: Azeliragon

Phase 1, Phase 2

Cantex Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 5 other locations

ONIVYDE + LV + 5-FU chemotherapy regimen in patients with advanced pancreatic cancer and to determine the recommended dose for the ...

Active, not recruiting
Pancreatic Cancer
Biological: XB2001 or Placebo

Phase 1, Phase 2

XBiotech

Pittsburgh, Pennsylvania, United States and 27 other locations

and clinical activity of AB680 in combination with zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...

Active, not recruiting
Advanced Pancreatic Cancer
Drug: Zimberelimab
Drug: Gemcitabine

Phase 1

Arcus Biosciences
Arcus Biosciences

Pittsburgh, Pennsylvania, United States and 15 other locations

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...

Enrolling
Locally Advanced Pancreatic Cancer
Device: RenovoCath
Drug: nab-paclitaxel

Phase 3

RenovoRx

Pittsburgh, Pennsylvania, United States and 41 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Pittsburgh, Pennsylvania, United States and 59 other locations

and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...

Active, not recruiting
Neoplasm of Lung
Neoplasms Pancreatic
Drug: Gemcitabine - 21 day cycle
Drug: 9-ING-41

Phase 2

Actuate Therapeutics

Pittsburgh, Pennsylvania, United States and 65 other locations

administered orally as monotherapy in patients with advanced solid tumors with gene alterations in the RAS- MAPK pathway for whom there are ...

Enrolling
Solid Tumor, Adult
Pancreatic Cancer
Drug: IK-595

Phase 1

Ikena Oncology

Pittsburg, Pennsylvania, United States and 14 other locations

of care. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic...

Active, not recruiting
Advanced Cancer
Gastric Cancer
Drug: mFOLFOX6
Drug: Gemcitabine

Phase 1, Phase 2

Transcenta

Pittsburgh, Pennsylvania, United States and 17 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Enrolling
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Pittsburgh, Pennsylvania, United States and 56 other locations

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