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Find clinical trials for Pancreatic Cancer in Pittsburgh, PA

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Related conditions:

Adenocarcinoma
Cancer
Carcinoma
Colorectal Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Squamous Cell Carcinoma of Head and Neck

Pancreatic Cancer trials near Pittsburgh, PA, USA:

Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer (LAPIS)

with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic...

Active, not recruiting
Pancreatic Cancer Non-resectable
Drug: Pamrevlumab + Gemcitabine + Nab-paclitaxel or Pamrevlumab + FOLFIRINOX
Drug: Placebo + Gemcitabine + Nab-paclitaxel or Placebo + FOLFIRINOX

Phase 3

FibroGen
FibroGen

Pittsburgh, Pennsylvania, United States and 89 other locations

ONIVYDE + LV + 5-FU chemotherapy regimen in patients with advanced pancreatic cancer and to determine the recommended dose for the ...

Active, not recruiting
Pancreatic Cancer
Biological: XB2001 or Placebo

Phase 1, Phase 2

XBiotech

Pittsburgh, Pennsylvania, United States and 27 other locations

to determine the safety and preliminary evidence of a therapeutic effect of azeliragon in patients refractory to prior treatment of metastatic pancreatic...

Enrolling
Metastatic Pancreatic Cancer
Drug: Azeliragon

Phase 1, Phase 2

Cantex Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 5 other locations

and clinical activity of AB680 in combination with Zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...

Enrolling
Advanced Pancreatic Cancer
Drug: Zimberelimab
Drug: Gemcitabine

Phase 1

Arcus Biosciences
Arcus Biosciences

Pittsburgh, Pennsylvania, United States and 17 other locations

treatment combinations in participants with metastatic Pancreatic Ductal Adenocarcinoma (PDAC).Two cohorts will be enrolled in parallel in t...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Fluorouracil
Drug: RO6874281

Phase 1, Phase 2

Roche
Roche

Pittsburgh, Pennsylvania, United States and 26 other locations

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma whic...

Enrolling
Locally Advanced Pancreatic Cancer
Device: RenovoCath
Drug: nab-paclitaxel

Phase 3

RenovoRx

Pittsburgh, Pennsylvania, United States and 38 other locations

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...

Active, not recruiting
Breast Cancer
Colon Cancer
Biological: E-602
Biological: Cemiplimab

Phase 1, Phase 2

Palleon Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 12 other locations

and efficacy of 9-ING-41, a potent GSK-3β inhibitor, as a single agent and in combination with cytotoxic agents, in patients with refractory cancers...

Active, not recruiting
Neoplasms Pancreatic
Pancreatic Adenocarcinoma
Drug: Gemcitabine - 21 day cycle
Drug: Lomustine

Phase 2

Actuate Therapeutics

Pittsburgh, Pennsylvania, United States and 65 other locations

This is a Phase 1, FIH, Dose Escalation and Dose Expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) e...

Enrolling
Pancreatic Cancer
Colorectal Cancer
Drug: IK-595

Phase 1

Ikena Oncology

Pittsburgh, Pennsylvania, United States and 4 other locations

nivolumab or standard of care. It is being tested against advanced and/or metastatic solid tumors including gastric, gastroesophageal junction, pancreatic...

Enrolling
Advanced Cancer
Gastric Cancer
Drug: Albumin-Bound Paclitaxel
Drug: Gemcitabine

Phase 1, Phase 2

Transcenta

Pittsburgh, Pennsylvania, United States and 18 other locations

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