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and clinical activity of AB680 in combination with Zimberelimab (AB122), nab-paclitaxel and gemcitabine in participants with advanced pancreatic...
Phase 1
San Antonio, Texas, United States of America and 17 other locations
The purpose of this study is to characterize the safety and tolerability of ALTA3263 in adults with advanced solid tumors with KRAS mutation...
Phase 1
San Antonio, Texas, United States and 1 other location
is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...
Phase 1
San Antonio, Texas, United States and 16 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....
Phase 1
San Antonio, Texas, United States and 15 other locations
The study is a first-in-human (FIH), open-label, multi-center phase 1/2 study of TSN1611 in subjects with KRAS G12D mutant advanced solid tumors...
Phase 1, Phase 2
San Antonio, Texas, United States and 2 other locations
AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 ef...
Phase 1
San Antonio, Texas, United States and 1 other location
This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...
Phase 1, Phase 2
San Antonio, Texas, United States and 12 other locations
dose-escalation, safety, pharmacokinetics (PK), and biomarker study of CBX-12 in subjects with advanced or metastatic refractory solid tumors...
Phase 1, Phase 2
San Antonio, Texas, United States and 3 other locations
administered orally as monotherapy in patients with advanced solid tumors with gene alterations in the RAS- MAPK pathway for whom there are ...
Phase 1
San Antonio, Texas, United States and 7 other locations
A Phase 1/2 study of MRTX1133 in solid tumors harboring a KRAS G12D mutation....
Phase 1
San Antonio, Texas, United States and 15 other locations
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