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Find clinical trials for Prostate Cancer in Birmingham, AL

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Related conditions:

Prostatic Cancer
Cancer
Carcinoma
Hypersensitivity
Recurrence
Adenocarcinoma
Castration-Resistant Prostatic Cancer

Prostate Cancer trials near Birmingham, AL, USA:

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

and abiraterone in patients with metastatic castration-resistant prostate cancer (mCRPC) who have received no prior cytotoxic chemo ...

Active, not recruiting
Metastatic Castration-resistant Prostate Cancer
Drug: abiraterone acetate
Drug: olaparib

Phase 3

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 131 other locations

clinical efficacy in participants with metastatic hormone-sensitive prostate cancer (mHSPC) by progression-free survival.The resear...

Active, not recruiting
Metastatic Hormone-sensitive Prostate Cancer
Drug: Darolutamide (BAY1841788, Nubeqa)
Other: ADT

Phase 2

Bayer
Bayer

Homewood, Alabama, United States and 28 other locations

The purpose of this study is to evaluate the efficacy and safety of apalutamide in adult men with high-risk non-metastatic castration-resistant prostate...

Active, not recruiting
Prostatic Neoplasms
Drug: Placebo
Drug: Apalutamide

Phase 3

Aragon Pharmaceuticals

Birmingham, Alabama, United States and 388 other locations

in participants with high-risk, localized or locally advanced prostate cancer receiving primary radiation therapy results in an imp...

Active, not recruiting
Prostatic Neoplasms
Radiation: 74-80 Grays (units of radiation)
Drug: GnRH (agonist)

Phase 3

Aragon Pharmaceuticals

Homewood, Alabama, United States and 271 other locations

this study is to assess the safety, tolerability and preliminary efficacy of CC-94676 in men with progressive metastatic castration resistant prostate...

Enrolling
Prostatic Neoplasms
Drug: CC-94676
Drug: CC1083610

Phase 1

Celgene
Celgene

Birmingham, Alabama, United States and 24 other locations

The purpose of this study was to evaluate the efficacy of enzalutamide plus androgen deprivation therapy (ADT) as measured by radiographic progressio...

Active, not recruiting
Metastatic Hormone Sensitive Prostate Cancer
Drug: Placebo
Drug: Enzalutamide

Phase 3

Astellas
Astellas

Homewood, Alabama, United States and 202 other locations

prednisone in treating patients with castration-resistant metastatic prostate cancer. Androgens can cause the growth of prostate...

Active, not recruiting
Hormone-resistant Prostate Cancer
Stage IV Prostate Cancer
Drug: prednisone
Drug: enzalutamide

Phase 3

Alliance for Clinical Trials in Oncology
Alliance for Clinical Trials in Oncology

Birmingham, Alabama, United States and 538 other locations

The purpose of this study is to compare overall survival in newly diagnosed metastatic prostate cancer patients randomly assigned t...

Active, not recruiting
Prostate Cancer
Drug: Bicalutamide
Drug: TAK-700

Phase 3

SWOG Cancer Research Network

Birmingham, Alabama, United States and 559 other locations

The purpose of the study is to evaluate the safety and efficacy of talazoparib in combination with enzalutamide compared with placebo in combination...

Active, not recruiting
Prostate Cancer
Drug: Placebo plus enzalutamide
Drug: talazoparib plus enzalutamide

Phase 3

Pfizer
Pfizer

Birmingham, Alabama, United States and 313 other locations

The purpose of this study is to assess enzalutamide plus leuprolide in patients with high-risk nonmetastatic prostate cancer progre...

Active, not recruiting
Hormone Sensitive Prostate Cancer
Prostate Cancer
Drug: Enzalutamide
Drug: Placebo (No longer applicable in Open Label study period)

Phase 3

Pfizer
Pfizer

Birmingham, Alabama, United States and 254 other locations

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