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Find clinical trials for Prostate Cancer in Charlotte, NC

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Related conditions:

Prostatic Cancer
Cancer
Carcinoma
Hypersensitivity
Adenocarcinoma
Recurrence
Breast Cancer

Prostate Cancer trials near Charlotte, NC, USA:

A Trial of Androgen Deprivation, Docetaxel, and Enzalutamide for Metastatic Prostate Cancer

of enzalutamide in the treatment of subjects with metastatic prostate cancer. The purpose of this study is to assess if ADT + docet...

Active, not recruiting
Prostate Adenocarcinoma
Prostate Cancer
Drug: ADT+Docetaxel+Enzalutamide

Phase 2

Wake Forest University (WFU)
Wake Forest University (WFU)

Charlotte, North Carolina, United States

Prostate cancer has the second highest incidence rate and is the fifth leading cause of cancer-related deaths among men wo ...

Enrolling
Metastatic Castration-Resistant Prostate Cancer
Drug: ABBV-969

Phase 1

AbbVie
AbbVie

Huntersville, North Carolina, United States of America and 17 other locations

the safety and preliminary antitumor activity of ORIC-944 as a single agent and in combinations with ARPIs in patients with metastatic prostate...

Enrolling
Metastatic Prostate Cancer
Drug: Darolutamide (Nubeqa®) 300 mg tablets
Drug: ORIC-944

Phase 1

Oric Pharmaceuticals

Charlotte, North Carolina, United States and 15 other locations

second-line androgen receptor (AR) directed therapy with enzalutamide or docetaxel (chemotherapy) for treating metastatic castration-resistant prostate...

Enrolling
Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Drug: PF-06821497
Drug: Enzalutamide

Phase 3

Pfizer
Pfizer

Salisbury, North Carolina, United States of America and 156 other locations

The purpose of this study is to evaluate the efficacy and safety of apalutamide in adult men with high-risk non-metastatic castration-resistant prostate...

Active, not recruiting
Prostatic Neoplasms
Drug: Apalutamide
Drug: Placebo

Phase 3

Aragon Pharmaceuticals

Concord, North Carolina, United States and 388 other locations

cemiplimab, or in combination with REGN5678. REGN4336, cemiplimab and REGN5678 are a type of treatment for cancer called immunotherapy,and ...

Enrolling
Metastatic Castration-resistant Prostate Cancer
Drug: Cemiplimab
Drug: Sarilumab

Phase 1, Phase 2

Regeneron Pharmaceuticals
Regeneron Pharmaceuticals

Charlotte, North Carolina, United States and 11 other locations

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutam...

Enrolling
Prostate Cancer
Drug: prednisone
Drug: enzalutamide

Phase 2

Astellas
Astellas

Charlotte, North Carolina, United States and 235 other locations

and tolerability of xaluritamig monotherapy in adult participants with high-risk biochemical recurrent (BCR) nonmetastatic castration-sensitive prostate...

Enrolling
Non-metastatic Castration-sensitive Prostate Cancer
High Risk Biochemical Recurrence of Non-metastatic Castration-sensitive Prostate Cancer
Drug: Xaluritamig

Phase 1

Amgen
Amgen

Charlotte, North Carolina, United States and 7 other locations

The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetax...

Enrolling
Prostate Cancer
Drug: Radium-223
Drug: Docetaxel 60 mg/m2

Phase 3

Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Monroe, North Carolina, United States and 70 other locations

This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling tim...

Active, not recruiting
Prostate Cancer
Drug: LHRH Analogue
Drug: Prednisone

Phase 3

Alliance Foundation Trials

Charlotte, North Carolina, United States and 68 other locations

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