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Find clinical trials for Prostate Cancer in Pittsburgh, PA

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Related conditions:

Prostatic Cancer
Cancer
Carcinoma
Hypersensitivity
Adenocarcinoma
Recurrence
Castration-Resistant Prostatic Cancer

Prostate Cancer trials near Pittsburgh, PA, USA:

Randomized Controlled Trial of CAN-2409 Immunotherapy During Active Surveillance for Prostate Cancer (ULYSSES)

The purpose of this study is to evaluate the effectiveness of CAN-2409 immunotherapy in patients undergoing active surveillance for localized prostate...

Active, not recruiting
Prostate Cancer
Biological: placebo
Biological: aglatimagene besadenovec

Phase 2

Candel Therapeutics

Pittsburgh, Pennsylvania, United States and 22 other locations

A Phase 1/2 study to evaluate the safety and efficacy of ARV-766 given by mouth alone or in combination with abiraterone in men with metastatic prostate...

Enrolling
Prostate Cancer Metastatic
Drug: ARV-766 + Abiraterone Part C&D
Drug: ARV-766 Part A&B

Phase 1, Phase 2

Arvinas
Arvinas

Pittsburgh, Pennsylvania, United States and 22 other locations

the SpaceOAR Vue System in reducing late gastrointestinal (GI) toxicity in subjects undergoing Stereotactic Body Radiotherapy (SBRT) to treat prostate...

Enrolling
Prostate Cancer
Device: SpaceOAR Vue System
Boston Scientific
Boston Scientific

Pittsburgh, Pennsylvania, United States and 27 other locations

Locations recently updated

Evaluate the safety and tolerability of AMG 509 in adult participants and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2...

Enrolling
Prostate Cancer
Drug: Abiraterone
Drug: Enzalutamide

Phase 1

Amgen
Amgen

Pittsburgh, Pennsylvania, United States and 48 other locations

of vudalimab (XmAb20717) alone or in combination with standard of care anticancer therapies in patients with metastatic castration-resistant prostate...

Enrolling
Metastatic Castration-Resistant Prostate Cancer
Biological: vudalimab monotherapy
Combination Product: vudalimab + olaparib

Phase 2

Xencor
Xencor

Pittsburgh, Pennsylvania, United States and 16 other locations

enzalutamide or abiraterone/prednisone alone in asymptomatic or mildly symptomatic subjects with progressive, metastatic castration-resistant prostate...

Active, not recruiting
Metastatic Prostate Cancer
Metastatic Castration-resistant Prostate Cancer
Drug: Tazemetostat
Drug: Abiraterone/prednisone

Phase 1, Phase 2

Epizyme

Pittsburgh, Pennsylvania, United States and 23 other locations

has in treatment of patients with metastatic castrate resistant prostate cancer (mCRPC).The hypothesis for this trial is that caboz...

Enrolling
Prostate Cancer
Drug: Cabozantinib

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Pittsburgh, Pennsylvania, United States and 4 other locations

therapy in participants with metastatic castration resistant prostate cancer (mCRPC). There will be ten cohorts in this study: Coho...

Enrolling
Metastatic Castration-Resistant Prostate Cancer
Drug: Enzalutamide 160 mg
Drug: Olaparib 400 mg

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 32 other locations

Locations recently updated

The purpose of this study is to collect long term safety data in subjects who are continuing to derive clinical benefit from treatment with Enzalutam...

Enrolling
Prostate Cancer
Drug: prednisone
Drug: enzalutamide

Phase 2

Astellas
Astellas

Pittsburgh, Pennsylvania, United States and 225 other locations

The purpose of this study is to evaluate the efficacy and safety of apalutamide in adult men with high-risk non-metastatic castration-resistant prostate...

Active, not recruiting
Prostatic Neoplasms
Drug: Apalutamide
Drug: Placebo

Phase 3

Aragon Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 388 other locations

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