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Find clinical trials for Triple Negative Breast Cancer in Birmingham, AL

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Epithelial Carcinoma

Triple Negative Breast Cancer trials near Birmingham, AL, USA:

Circulating Tumor DNA Enriched, Genomically Directed Post-neoadjuvant Trial for Patients With Residual Triple Negative Breast Cancer (PERSEVERE)

This is a 3-arm study stratified by plasma ctDNA. Patients with residual TNBC disease after pre-operative therapy will be assigned to 1 of 3 Arms bas...

Active, not recruiting
Breast Cancer
Triple Negative Breast Cancer
Drug: Inavolisib
Drug: Talazoparib

Phase 2

Bryan Schneider, MD

Birmingham, Alabama, United States and 12 other locations

avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage I...

Enrolling
Stage IIIA Breast Cancer
Recurrent Breast Carcinoma
Biological: Utomilumab
Biological: Anti-OX40 Antibody PF-04518600

Phase 2

Hope Rugo, MD

Birmingham, Alabama, United States and 11 other locations

or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after su...

Enrolling
Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

Phase 3

Gilead Sciences
Gilead Sciences

Birmingham, Alabama, United States of America and 176 other locations

monotherapy versus olaparib in combination with an inhibitor of WEE1 (adavosertib \[AZD1775\]) in second or third line setting in patients with Triple...

Active, not recruiting
Metastatic Triple Negative Breast Cancer
Drug: Olaparib Continuous (28-Day cycle) 300 mg BD.
Drug: Adavosertib 150 mg BD + olaparib 200 mg BD (21-day cycle).

Phase 2

AstraZeneca
AstraZeneca

Birmingham, Alabama, United States and 140 other locations

Locations recently updated

This study will test the safety of a drug called PF-08046054/SGN-PDL1V alone and with pembrolizumab in participants with solid tumors. It wi ...

Enrolling
Ovarian Neoplasms
Gastric Cancer
Drug: pembrolizumab
Drug: PF-08046054

Phase 1

Seagen
Seagen

Birmingham, Alabama, United States and 41 other locations

in treating advanced or metastatic androgen receptor-positive (AR+) triple negative breast cancer (TNBC) or estro ...

Enrolling
Metastatic Breast Cancer
Drug: Mifepristone
Drug: Enzalutamide

Phase 2

Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Birmingham, Alabama, United States and 11 other locations

tumors....

Enrolling
Endometrial Cancer
Triple Negative Breast Cancer
Biological: NM32-2668

Phase 1

Numab Therapeutics

Birmingham, Alabama, United States and 7 other locations

to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast...

Active, not recruiting
Locally Advanced Breast Cancer
Metastatic Breast Cancer
Drug: U3-1402

Phase 2

SCRI Development Innovations

Birmingham, Alabama, United States and 10 other locations

and clinical antitumor activity of XB002 administered IV q3w alone and in combination with nivolumab to subjects with advanced solid tumors....

Active, not recruiting
Endometrial Cancer
Tissue Factor-Expressing Solid Tumors
Drug: XB002
Drug: Nivolumab

Phase 1

Exelixis
Exelixis

Birmingham, Alabama, United States and 94 other locations

followed by immunotherapy, for patients with brain metastases from triple negative or BRCA-mutated breast cancers...

Enrolling
Breast Cancer
Brain Metastases, Adult
Drug: Durvalumab
Radiation: Stereotactic Radiosurgery

Phase 1, Phase 2

Colette Shen

Birmingham, Alabama, United States and 6 other locations

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