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hormone-receptor (HR) positive and HER2 negative advanced breast cancer, the most common subtype of breast cancer...
Phase 1
London, United Kingdom and 7 other locations
of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple...
Phase 1, Phase 2
London, United Kingdom and 31 other locations
or paclitaxel (cohort 1) or with sacituzumab govitecan-hziy (cohort 2) in patients with non-surgically removable locally advanced or metastatic triple...
Phase 2
London, London, City of, England and 44 other locations
The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer...
Phase 2
London, United Kingdom and 4 other locations
PHOENIX is a window of opportunity (WOP), open-label, multi-centre, phase IIa trial comprising multiple non-comparative treatment cohorts with patien...
Phase 2
London, United Kingdom and 8 other locations
This study will assess the efficacy and safety of Niraparib in participants with either tumor mutation in the BRCA gene (tBRCAmut) HER2- breast...
Phase 3
London, United Kingdom and 199 other locations
non-metastatic, high-risk (node positive and/or tumour size ≥ 2cm), triple negative breast cancer. The study aims...
Phase 2
London, United Kingdom
This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement ...
Phase 2, Phase 3
London, United Kingdom and 29 other locations
levels in combination with chemotherapeutic agents in the first- and second-line treatment of participants with locally advanced/metastatic triple...
Phase 2
London, United Kingdom and 16 other locations
the efficacy and safety of atezolizumab plus chemotherapy compared with placebo plus chemotherapy in patients with inoperable recurrent triple...
Phase 3
London, United Kingdom and 135 other locations
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