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hormone-receptor (HR) positive and HER2 negative advanced breast cancer, the most common subtype of breast cancer...
Phase 1
London, United Kingdom and 7 other locations
or paclitaxel (cohort 1) or with sacituzumab govitecan-hziy (cohort 2) in patients with non-surgically removable locally advanced or metastatic triple...
Phase 2
Leicester, United Kingdom and 44 other locations
of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple...
Phase 1, Phase 2
London, United Kingdom and 46 other locations
residual disease following patients standard primary treatment for triple negative breast cancer, and will assess...
Phase 2
London, United Kingdom and 16 other locations
PHOENIX is a window of opportunity (WOP), open-label, multi-centre, phase IIa trial comprising multiple non-comparative treatment cohorts with patien...
Phase 2
London, United Kingdom and 8 other locations
The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer...
Phase 2
London, United Kingdom and 4 other locations
non-metastatic, high-risk (node positive and/or tumour size ≥ 2cm), triple negative breast cancer. The study aims...
Phase 2
London, United Kingdom
This study will assess the efficacy and safety of Niraparib in participants with either tumor mutation in the BRCA gene (tBRCAmut) HER2- breast...
Phase 3
London, United Kingdom and 226 other locations
This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement ...
Phase 2, Phase 3
London, United Kingdom and 29 other locations
the efficacy and safety of atezolizumab plus chemotherapy compared with placebo plus chemotherapy in patients with inoperable recurrent triple...
Phase 3
London, United Kingdom and 137 other locations
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