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Find clinical trials for Triple Negative Breast Cancer in London, England

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Related conditions:

Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Melanoma

Triple Negative Breast Cancer trials near London, England, GBR:

PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer

hormone-receptor (HR) positive and HER2 negative advanced breast cancer, the most common subtype of breast cancer...

Enrolling
Locally Advanced Breast Cancer
HER2-positive Breast Cancer
Drug: Avelumab
Drug: Palbociclib

Phase 1

Royal Marsden NHS Foundation Trust

London, United Kingdom and 7 other locations

or paclitaxel (cohort 1) or with sacituzumab govitecan-hziy (cohort 2) in patients with non-surgically removable locally advanced or metastatic triple...

Active, not recruiting
Triple-Negative Breast Cancer
Drug: Sacituzumab Govitecan-hziy
Drug: Magrolimab

Phase 2

Gilead Sciences
Gilead Sciences

Leicester, United Kingdom and 44 other locations

of durvalumab in combination with novel oncology therapies with or without paclitaxel and durvalumab + paclitaxel for first-line metastatic triple...

Enrolling
Triple Negative Breast Neoplasms
Drug: Capivasertib
Drug: Datopotamab deruxtecan

Phase 1, Phase 2

AstraZeneca
AstraZeneca

London, United Kingdom and 46 other locations

residual disease following patients standard primary treatment for triple negative breast cancer, and will assess...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Pembrolizumab

Phase 2

Institute of Cancer Research, United Kingdom

London, United Kingdom and 16 other locations

PHOENIX is a window of opportunity (WOP), open-label, multi-centre, phase IIa trial comprising multiple non-comparative treatment cohorts with patien...

Enrolling
Breast Neoplasm
Drug: Durvalumab
Drug: AZD6738

Phase 2

Institute of Cancer Research, United Kingdom

London, United Kingdom and 8 other locations

The purpose of this study is to find out how effective the combination of crizotinib and fulvestrant is in shrinking lobular breast cancer...

Active, not recruiting
Gastric Cancer
Lobular Breast Carcinoma
Drug: Crizotinib Oral Capsule [Xalkori]
Drug: Fulvestrant 50 MG/ML Prefilled Syringe [Faslodex or generic]

Phase 2

Royal Marsden NHS Foundation Trust

London, United Kingdom and 4 other locations

non-metastatic, high-risk (node positive and/or tumour size ≥ 2cm), triple negative breast cancer. The study aims...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Paclitaxel
Drug: Doxorubicin

Phase 2

Queen Mary University of London

London, United Kingdom

This study will assess the efficacy and safety of Niraparib in participants with either tumor mutation in the BRCA gene (tBRCAmut) HER2- breast...

Active, not recruiting
Neoplasms, Breast
Drug: Niraparib
Drug: Placebo

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

London, United Kingdom and 226 other locations

This neoadjuvant trial for patients with TNBC and/or gBRCA breast cancer, aims to investigate the safety and efficacy (improvement ...

Enrolling
Breast Cancer
Drug: Paclitaxel and Carboplatin
Drug: Olaparib

Phase 2, Phase 3

NHS Foundation Trust
NHS Foundation Trust

London, United Kingdom and 29 other locations

the efficacy and safety of atezolizumab plus chemotherapy compared with placebo plus chemotherapy in patients with inoperable recurrent triple...

Active, not recruiting
Triple Negative Breast Neoplasms
Drug: Placebo
Drug: Capecitabine

Phase 3

Roche
Roche

London, United Kingdom and 136 other locations

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