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The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer...
Phase 2
Nashville, Tennessee, United States and 8 other locations
oral immuno-oncology product candidate targeting immune-suppressive tumor-associated myeloid cells through selective inhibition of phosphoin ...
Phase 2
Nashville, Tennessee, United States and 23 other locations
avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage I...
Phase 2
Nashville, Tennessee, United States and 11 other locations
to assess the safety, tolerability, and pharmacokinetics, and to identify the optimal dose of ADRX-0706 in patients with select advanced solid tumors...
Phase 1
Nashville, Tennessee, United States and 20 other locations
This study is one single group of participants with non-small cell lung cancer (NSCLC) who have not been cured by other treatments. It is th...
Phase 1
Nashville, Tennessee, United States and 17 other locations
levels in combination with chemotherapeutic agents in the first- and second-line treatment of participants with locally advanced/metastatic triple...
Phase 2
Nashville, Tennessee, United States and 63 other locations
This is a Phase III, randomised, open-label, 2 arm, multicentre, international study assessing the efficacy and safety of Dato-DXd compared with ICC...
Phase 3
Nashville, Tennessee, United States and 225 other locations
previously untreated, locally advanced, inoperable or metastatic triple-negative breast cancer whose tumors...
Phase 3
Nashville, Tennessee, United States and 516 other locations
the RP2D. The RP2D will be administered to 3 cohorts of patients in the Dose Expansion Phase.* Cohort A: Advanced or Metastatic Triple Negative...
Phase 1, Phase 2
Nashville, Tennessee, United States and 15 other locations
with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors...
Phase 3
Nashville, Tennessee, United States and 505 other locations
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