Alaska Heart and Vascular Institute | Anchorage, AK

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Metoprolol Succinate
Omecamtiv Mecarbil

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Active trials

6 of 8 total trials

A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease (COORDINATE)

COORDINATE-Diabetes is a cluster-randomized clinical trial to test the effectiveness of an innovative, clinic-level educational intervention to impro...

Active, not recruiting
Cardiovascular Diseases
Diabetes Mellitus, Type 2
Other: Intense Education Intervention
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The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to collect long-term safety and tolerability data for aficamten (CK-3773274)

Symptomatic Hypertrophic Cardiomyopathy (HCM)
Drug: CK-3773274 (5 - 20 mg)

The purpose of this study is to compare the efficacy and safety of aficamten (CK-3773274) compared with metoprolol succinate in adults with symptomat...

Obstructive Hypertrophic Cardiomyopathy (oHCM)
Drug: Metoprolol succinate (50 mg, 100 mg, 150 mg and 200 mg)
Drug: Aficamten (CK-3773274) (5 mg, 10 mg, 15 mg and 20 mg)

This clinical trial will study the effects of aficamten (versus placebo) on the quality of life, exercise capacity, and clinical outcomes of patients...

Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Drug: Aficamten
Drug: Placebo

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Overweight and Obesity
Drug: Retatrutide
Drug: Placebo

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