Alaska Heart and Vascular Institute | Anchorage, AK

Research site
3841 Piper Street Suite T-100, Anchorage, Alaska, United States of America
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5 of 7
Status: Active
Trial type: Interventional
Funder type: Industry

A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease (COORDINATE)

COORDINATE-Diabetes is a cluster-randomized clinical trial to test the effectiveness of an innovative, clinic-level educational intervention to impro...

Active, not recruiting
Cardiovascular Diseases
Diabetes Mellitus, Type 2
Other: Intense Education Intervention

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to collect long-term safety and tolerability data for aficamten (CK-3773274)

Symptomatic Hypertrophic Cardiomyopathy (HCM)
Drug: CK-3773274 (5 - 20 mg)

The purpose of this study is to compare the efficacy and safety of aficamten (CK-3773274) compared with metoprolol succinate in adults with symptomat...

Obstructive Hypertrophic Cardiomyopathy (oHCM)
Drug: Placebo to match metoprolol succinate
Drug: Aficamten (CK-3773274) (5 mg, 10 mg, 15 mg and 20 mg)

This clinical trial will study the effects of aficamten (versus placebo) on the quality of life, exercise capacity, and clinical outcomes of patients...

Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Drug: Placebo
Drug: Aficamten

Trial conditions

Cardiomyopathies (4 trials)
Hypertrophic Cardiomyopa... (4 trials)
Hypertrophy (4 trials)
Cardiovascular Diseases (2 trials)
Atherosclerosis (1 trial)
Diabetes Mellitus (1 trial)
Heart Failure (1 trial)
Type 2 Diabetes Mellitus (1 trial)

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