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Alaska Heart and Vascular Institute | Anchorage, AK

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Top treatments

Aficamten
Metoprolol Succinate
CK-3773274
Retatrutide
Omecamtiv Mecarbil

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Active trials

6 of 8 total trials

A 12 Month Site Randomized Trial in Adults With Type 2 Diabetes Mellitus and History of Cardiovascular Disease (COORDINATE)

COORDINATE-Diabetes is a cluster-randomized clinical trial to test the effectiveness of an innovative, clinic-level educational intervention to impro...

Active, not recruiting
Cardiovascular Diseases
Diabetes Mellitus, Type 2
Other: Intense Education Intervention
Locations recently updated

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to collect long-term safety and tolerability data for aficamten (CK-3773274)

Invitation-only
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Drug: CK-3773274 (5 - 20 mg)

The purpose of this study is to compare the efficacy and safety of aficamten (CK-3773274) compared with metoprolol succinate in adults with symptomat...

Enrolling
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Drug: Metoprolol succinate (50 mg, 100 mg, 150 mg and 200 mg)
Drug: Aficamten (CK-3773274) (5 mg, 10 mg, 15 mg and 20 mg)

This clinical trial will study the effects of aficamten (versus placebo) on the quality of life, exercise capacity, and clinical outcomes of patients...

Enrolling
Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
Drug: Aficamten
Drug: Placebo

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Enrolling
Overweight and Obesity
Drug: Retatrutide
Drug: Placebo

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