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BI 456906
Tirzepatide
MK-0616

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Active trials

6 of 8 total trials

A Study of MK-0616 (Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

The goal of this study is to evaluate the efficacy, safety, and tolerability of MK-0616 in adult participants with hypercholesterolemia. The primary...

Active, not recruiting
Hypercholesterolemia
Familial Hypercholesterolemia
Drug: MK-0616
Drug: Placebo

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing treatment...

Active, not recruiting
Type 2 Diabetes
Drug: Antihyperglycemic medication
Drug: Tirzepatide

The purpose of this study is to learn about the safety and immune effects of a pneumococcal vaccine in adults. This vaccine can possibly provide prot...

Enrolling
Pneumococcal Disease
Biological: 20-valent pneumococcal conjugate vaccine (20vPnC)
Biological: Multivalent Pneumococcal Vaccine - Formulation 2

This study is open to adults who are at least 18 years old and have a body mass index of 27 kg/m² or more. People can take part if they have type 2 d...

Active, not recruiting
Obesity
Diabetes Mellitus, Type 2
Drug: Survodutide
Drug: Placebo

This study is open to adults who are at least 18 years old and have* a body mass index (BMI) of 30 kg/m² or more, or* a BMI of 27 kg/m² or more and a...

Active, not recruiting
Obesity
Drug: survodutide
Drug: Placebo

An antibody is a substance your body makes to fight off infection. This study will explore the safety and antibody response of a vaccine to prevent s...

Enrolling
Clostridoides Difficile Associated Disease
Biological: C. difficile vaccine (previously studied formulation).
Biological: C. difficile vaccine formulation 1.

Trial sponsors

Merck Sharp & Dohme (MSD) logo
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