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Cytisinicline
Reloxaliase
Allopurinol
Orforglipron
Retatrutide
LY3502970

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Active trials

9 of 16 total trials

A Study About Modified RNA Vaccines Against Influenza in Healthy Adults

The purpose of this study is to learn if modified RNA (modRNA) vaccines for the prevention of influenza are:* safe; and* how these vaccines produce a...

Active, not recruiting
Influenza, Human
Biological: Influenza ModRNA Vaccine
Biological: Quadrivalent Influenza Vaccine (QIV)

The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabete...

Active, not recruiting
Chronic Kidney Disease
Overweight
Drug: Orforglipron
Drug: Insulin Glargine

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to...

Active, not recruiting
COVID-19
Influenza
Biological: COVID-19 Vaccine
Biological: Investigational influenza vaccine

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this clinical protocol is to learn about the safety, tolerability, and immunogenicity of new BNT162b2 RNA-based vaccine candidates tar...

Active, not recruiting
COVID-19
SARS-CoV-2 Infection
Biological: BNT162b2 (Omi XBB.1.5)
Biological: BNT162b2 (Omi JN.1)

The purpose of this phase 3 multicenter, randomized, double-blind, placebo-controlled rollover study is to evaluate the safety and long-term immunoge...

Enrolling
Chikungunya Virus Infection
Biological: Placebo booster
Biological: CHIKV VLP vaccine booster

Safety assessment of long-term 3 mg cytisinicline three times daily (TID) exposure for 52 weeks is the main purpose of this study, conducted in the U...

Enrolling
Vaping Cessation
Smoking Cessation
Drug: Cytisinicline

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Enrolling
Overweight and Obesity
Drug: Retatrutide
Drug: Placebo

The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the effi...

Enrolling
Hyperuricemia
Tophi
Drug: Allopurinol
Drug: Tigulixostat

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