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Alliance for Multispecialty Research, LLC | AMR Wichita East, KS

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Top conditions

Top treatments

QCZ484
Cytisinicline
Lasmiditan
Tirzepatide
Suzetrigine
LY573144
VX-548
PF-06865571
PF-05221304
LY3009104

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Active trials

12 of 51 total trials

A Study of DII235 in Adults With Elevated Lipoprotein(a)

The main purpose of this study is to determine the safety and efficacy of DII235 in adults with elevated lipoprotein(a).

Active, not recruiting
Lipoprotein Disorder
Drug: Saline
Drug: DII235

This is a multicenter, randomized, double-blind, factorial design Phase 2 study to evaluate the pharmacodynamics, safety and tolerability of a combin...

Enrolling
Hypercholesterolaemia
Drug: Inclisiran placebo
Drug: QCZ484 placebo

The purpose of this study is to evaluate the efficacy, safety and tolerability of QCZ484 or placebo, given subcutaneously, every 6 months, at differe...

Active, not recruiting
Hypertension
Drug: QCZ484
Other: Saline

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the p...

Enrolling
Hypertension (HTN)
Drug: QCZ484

The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.

Active, not recruiting
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Drug: Maridebart cafraglutide
Drug: Placebo

This is a Phase 4, post-market US study, evaluating the efficacy and safety of a single dose of the NVX-CoV2705 Omicron JN.1 COVID-19 vaccine. Approx...

Active, not recruiting
COVID-19
Sars-CoV-2 Infection
Biological: NVX-CoV2705
Biological: Placebo

This is a phase 3, randomized, placebo-controlled study of the efficacy and safety of enlicitide decanoate, an oral proprotein convertase subtilisin/...

Active, not recruiting
Arteriosclerosis
Hypercholesterolaemia
Drug: Enlicitide Decanoate
Drug: Placebo

The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine (SUZ) in participants with pain associated with diabet...

Enrolling
Diabetic Peripheral Neuropathic Pain
Drug: Suzetrigine
Drug: Placebo (matched to Pregabalin)

The purpose of this study is to evaluate the long-term safety and tolerability of SUZ and long-term effectiveness of SUZ in treating pain associated...

Active, not recruiting
Diabetic Peripheral Neuropathic Pain
Drug: Suzetrigine

The purpose of this phase 3 multicenter, randomized, double-blind, placebo-controlled rollover study is to evaluate the safety and long-term immunoge...

Active, not recruiting
Chikungunya Virus Infection
Biological: CHIKV VLP vaccine booster
Biological: Placebo booster

An antibody is a substance your body makes to fight off infection. This study will explore the safety and antibody response of a vaccine to prevent s...

Active, not recruiting
Clostridoides Difficile Associated Disease
Biological: C. difficile vaccine formulation 1.
Biological: C. difficile vaccine formulation 2.

Trial sponsors

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