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American Oncology Network | Genesis Cancer and Blood Institute

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Top treatments

Cyclophosphamide
Pembrolizumab
Atezolizumab
Sacituzumab
LY2835219
Doxorubicin
SBP-101
Tiragolumab
BMS-986012
LY4064809

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Active trials

12 of 15 total trials
Locations recently updated

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Researchers are looking for ways to treat germinal center B-cell-like diffuse large B-cell lymphoma (GCB DLBCL). DLBCL is a fast-growing blood cancer...

Enrolling
Lymphoma, Large B-Cell, Diffuse
Drug: Prednisone
Drug: Cyclophosphamide

This randomized Phase 3 open-label study will compare the efficacy of the T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif (I...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

The purpose of this study is to learn whether adding abemaciclib to abiraterone plus prednisone prolongs the time before prostate cancer gets worse....

Active, not recruiting
Cytochrome P-450
Antineoplastic Agents, Hormonal
Drug: Placebo for Abemaciclib
Drug: Abiraterone

The purpose of the study is to assess the efficacy and safety of the addition of Tersolisib (LY4064809/STX-478) to other anti-cancer drugs as first t...

Enrolling
Neoplasm Metastasis
Breast Neoplasms
Drug: Letrozole
Drug: Exemestane

The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with...

Enrolling
Extensive-Stage Small Cell Lung Cancer
Drug: Carboplatin
Drug: Etoposide

The goal of this randomized clinical trial is to learn if topical treatment with ATR04-484 can treat skin rash in patients undergoing EGFR inhibitor...

Enrolling
EGFR Inhibitor-associated Rash
Drug: ATR04-484
Drug: Vehicle

This is a Phase 3 Randomized, double-blind, Multiregional Study of Ivonescimab Combined with Chemotherapy Versus Pembrolizumab Combined with Chemothe...

Enrolling
Non-Small Cell Lung Cancer
Biological: Ivonescimab Injection
Biological: Pembrolizumab Injection

This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved...

Enrolling
Large B-cell Lymphoma
Drug: Fludarabine
Genetic: cemacabtagene ansegedleucel

The study is for patients with advanced melanoma who are eligible for standard therapy with Pembrolizumab.

Enrolling
Advanced Melanoma
Drug: EIK1001
Drug: Pembrolizumab (KEYTRUDA® )

The study is a randomized, double-blind, placebo-controlled, multicenter study of standard treatment with nab-paclitaxel and gemcitabine with or with...

Enrolling
Pancreatic Cancer Metastatic
Pancreatic Cancer Stage IV
Drug: Gemcitabine
Drug: Nab-paclitaxel

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versu...

Active, not recruiting
Triple Negative Breast Cancer
PD-L1 Positive
Drug: Pembrolizumab
Drug: Carboplatin

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) versus treatment of phy...

Active, not recruiting
Triple Negative Breast Cancer
PD-L1 Negative
Drug: Sacituzumab Govitecan-hziy
Drug: Paclitaxel

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