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Ark Clinical Research | Long Beach, CA

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Top treatments

Orforglipron
LY3502970
Retatrutide
LY3841136
Ritonavir
Eloralintide
Dupilumab
Sugar
Icovamenib
Tirzepatide

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Active trials

28 of 71 total trials

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes (Enith2)

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropi...

Enrolling
Obesity or Overweight
Type 2 Diabetes Mellitus
Combination Product: Enicepatide
Combination Product: Placebo

The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in...

Enrolling
Metabolic Dysfunction-Associated Steatotic Liver Disease
Drug: Tirzepatide
Drug: Placebo
Status recently updated

This study is researching an investigational drug, ALN-HSD called "study drug". This study is focused on participants who are known to have Metabolic...

Enrolling
Active, not recruiting
Metabolic Dysfunction-Associated SteatoHepatitis (MASH)
Drug: Placebo
Drug: ALN-HSD

This study is being done to look at the effect and safety of different doses of NNC0662-0419 in people living with type 2 diabetes when compared to p...

Enrolling
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: NNC0662-0419

The study is testing UBT251 in participants with type 2 diabetes. The purpose of this clinical study is to find out if UBT251 is effective and safe f...

Enrolling
Diabetes Mellitus, Type 2
Drug: UBT251
Drug: Semaglutide Placebo

The primary objective of this trial is to evaluate the dose-dependent and comparative effects of ECC4703 (low and high dose), ECC0509 (low and high d...

Enrolling
Metabolic Dysfunction-associated Steatohepatitis
Drug: Placebo
Drug: ECC4703

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants...

Enrolling
Overweight
Obesity
Drug: Eloralintide
Drug: Placebo

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with a placebo in participants with obesity or overwei...

Begins enrollment this month
Overweight
Obesity
Drug: Eloralintide
Drug: Placebo

The purpose of the studies is to evaluate the efficacy and safety of eloralintide in participants with moderate-to-severe obstructive sleep apnea and...

Enrolling
Overweight
Sleep Apnea, Obstructive
Drug: Placebo
Drug: Eloralintide

The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in participants with chronic rhinosinusitis and nasal polyps tr...

Enrolling
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Drug: Standard therapy for INCS
Drug: LY3650150

This study is being done to learn about the safety and effects of the study drugs, PF-08653945 and PF-08653944, when given alone or together for weig...

Active, not recruiting
Overweight and/or Obesity
Nutrition Disorders
Drug: PF-08653944
Drug: PF-08653945

The purpose of this study is to evaluate the safety and efficacy of solbinsiran in lowering triglycerides and other lipid measures compared to placeb...

Enrolling
Severe Hypertriglyceridemia
Drug: Placebo
Drug: Solbinsiran

This is a US, multi-center, randomized, double-blind, double-dummy, Phase 3b study to evaluate efficacy of remibrutinib (25 mg twice daily \[b.i.d.\]...

Active, not recruiting
Chronic Spontaneous Urticaria (CSU)
Drug: Placebo solution for injection
Drug: Dupilumab

This study is researching two experimental medicines, freneslerbart and mevonlerbart. Freneslerbart and mevonlerbart can be given alone or together....

Enrolling
Allergic Conjunctivitis
Drug: Placebo
Drug: Freneslerbart

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prev...

Active, not recruiting
Acute Gastroenteritis
Norovirus Acute Gastroenteritis
Biological: mRNA-1403
Biological: Placebo

The purpose of the study is to learn about the safety and effects of the study medicine (called ritlecitinib) for the treatment of chronic spontaneou...

Enrolling
Chronic Spontaneous Urticaria
Drug: Placebo - 100 mg
Drug: Ritlecitinib 50 mg

The primary objective of the study is to assess the efficacy of high dose fluticasone propionate (Fp)/albuterol sulfate (ABS) integrated electronic m...

Active, not recruiting
Asthma
Drug: TEV-56248
Drug: Albuterol sulfate
Locations recently updated

This study aims to find out whether a study medicine called survodutide helps people control their blood sugar. Adults who live with type 2 diabetes...

Enrolling
Type 2 Diabetes
Drug: Survodutide
Drug: Placebo
Locations recently updated

This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these cond...

Enrolling
Hypertension
Cardiovascular Diseases
Drug: Placebo matching Vicadrostat
Drug: Vicadrostat

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