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Ascension | St. Clair Nephrology Research

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Top conditions

Top treatments

Clazakizumab
Povetacicept
VX-147
Lesinurad
BI 764198
RGLS8429
RGLS4326
Cyclosporine
CXA-10
Tacrolimus

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Active trials

5 of 12 total trials

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

This is a two-part, phase 2b and phase 3 combined prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study.Part 1...

Enrolling
End Stage Kidney Disease
Drug: Placebo
Drug: CSL300

The purpose of this study is to evaluate the efficacy, safety, and tolerability of povetacicept in participants with primary membranous nephropathy (...

Enrolling
Primary Membranous Nephropathy
Drug: Tacrolimus
Drug: Povetacicept

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: VX-147
Drug: Placebo

The purpose of this study is to assess the safety and efficacy of up to 2 REACT/rilparencel injections in participants with T2DM and CKD.

Active, not recruiting
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT/ rilparencel)
Procedure: Sham Comparator

To Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Primary Immunoglobulin A Nephropathy

Active, not recruiting
Immunoglobulin A Nephropathy
Drug: Sibeprenlimab 400 mg
Drug: Placebo

Trial sponsors

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Vertex Pharmaceuticals logo
Boehringer Ingelheim logo
Bristol-Myers Squibb (BMS) logo
CSL Behring logo
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Ironwood Pharmaceuticals logo
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