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Ascension | St. Clair Nephrology Research

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Top treatments

VX-147
Lesinurad
BI 764198
RGLS8429
RGLS4326
Cyclosporine
CXA-10
Tacrolimus

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Active trials

2 of 8 total trials

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease (AMPLITUDE)

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and...

Enrolling
Chronic Kidney Diseases
Type 2 Diabetes Mellitus
Biological: Renal Autologous Cell Therapy (REACT)
Procedure: Sham Comparator

Trial sponsors

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Boehringer Ingelheim logo
Bristol-Myers Squibb (BMS) logo
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Ironwood Pharmaceuticals logo
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Vertex Pharmaceuticals logo

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