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Active trials

18 of 108 total trials

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow (REAL 8)

The study compares two medicines for treatment of children born small and who stay small, or with Turner Syndrome, Noonan Syndrome, or idiopathic sho...

SGA, Turner Syndrome, Noonan Syndrome, ISS
Drug: Norditropin®
Drug: Somapacitan
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This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Semaglutide
Drug: Placebo (semaglutide)

This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to insulin glargine (m...

Type 2 Diabetes
Drug: IcoSema
Drug: Insulin glargine

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant i...

Prader-Willi Syndrome
Drug: Pitolisant tablet
Other: Placebo tablet

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardio...

Active, not recruiting
Type 2 Diabetes Mellitus
Drug: Tirzepatide
Drug: Dulaglutide

The primary objective of this study is to evaluate the efficacy of Debio 4326 in suppressing serum luteinizing hormone (LH) to prepubertal levels 52...

Central Precocious Puberty
Drug: Debio 4326

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

This is a Phase 3 trial of cadisegliatin in participants with Type 1 Diabetes Mellitus.

Diabetes Mellitus, Type 1
Drug: Placebo
Drug: Cadisegliatin 800 mg BID

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD)...

Active, not recruiting
Atherosclerotic Cardiovascular Disease
Drug: Obicetrapib
Drug: Placebo

This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effect...

Device: Blood glucose meter
Device: Eversense CGM System

The objective of the study is to assess the safety and effectiveness of MiniMed™ 780G system in adult subjects with insulin-requiring type 2 diabetes...

Type 2 Diabetes Treated With Insulin
Device: MiniMed™ 780G Insulin Pump system

INHALE-3 is a Phase 4, randomized controlled trial (RCT) that will randomly assign participants ≥18 years of age with type 1 diabetes (T1D) using mul...

Active, not recruiting
Diabetes Mellitus, Type 1
Biological: Afrezza
Biological: Basal Insulin

The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with typ...

Type 1 Diabetes
Device: Subject's Current Diabetes Therapy
Device: 670G and 770G Insulin Pump

The study is designed to assess the efficacy, safety, tolerability, and transformation within the human body of INV-202 investigational drug in the t...

Active, not recruiting
Diabetic Kidney Disease
Drug: Placebo
Drug: INV-202

This is a multi-national trial. The goals of the trial are to study LUM-201 as a possible treatment for Pediatric Growth Hormone Deficiency (PGHD) an...

Active, not recruiting
Growth Hormone Deficiency
Drug: rhGH Norditropin® pen (34 µg/kg)
Drug: LUM-201

The goal of this study is to see if directing insulin to the liver will improve the low blood sugar that sometimes happens when injecting insulin in...

Diabetes Mellitus, Type 1
Drug: Lispro
Drug: HDV-Lispro

A Post Approval Study to Evaluate the Long-term Safety and Effectiveness of the Eversense® Continuous Glucose Monitoring (CGM) System over repeat ins...

Active, not recruiting
Diabetes Mellitus, Type 1
Diabetes Mellitus
Device: Eversense® CGM system

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Overweight and Obesity
Drug: Retatrutide
Drug: Placebo

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