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Atlantic Health System | Oncology Research

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Trials

20 of 62
Status: Active
Trial type: Interventional
Funder type: Industry

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7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

This is a Phase 4, U.S. only, multi-center study using a 7-day therapeutic response dose (TRD) of commercial Sucraid® to assess the response of treat...

Enrolling
CSID
Congenital Sucrase-Isomaltase Deficiency
Biological: Sucraid (sacrosidase) Oral Solution 8500 IU/mL

This Phase 3, multinational, single-arm, multicenter study will evaluate the efficacy and safety of UGN-102 as primary chemoablative therapy in patie...

Active, not recruiting
Bladder Cancer
Urothelial Carcinoma
Drug: UGN-102

The purpose of this study is to evaluate the efficacy and safety of ANV419 monotherapy or the combination of ANV419 with anti-PD1 antibody or with an...

Enrolling
Melanoma (Skin)
Advanced Solid Tumor
Drug: Ipilimumab
Drug: ANV419

The purpose of this study is to investigate experimental medication BMS-986253 in combination with Nivolumab or Nivolumab plus Ipilimumab in particip...

Active, not recruiting
Melanoma
Cancer
Biological: Ipilimumab
Other: Placebo

The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and...

Enrolling
Solid Tumors
Drug: Nivolumab
Drug: DF6002

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker pat...

Enrolling
Carcinoma, Non-Small-Cell Lung
Adenocarcinoma of Lung
Drug: Pemetrexed
Drug: Carboplatin

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of th...

Enrolling
Crohn's Disease
Drug: Mirikizumab

This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: CC-486
Drug: Venetoclax

The main purpose of this study is to establish the safety and the recommended dose of TRK-950 in combination with FOLFIRI, Gemcitabine / Cisplatin, G...

Enrolling
Solid Tumor
Epithelial Ovarian Cancer
Drug: Gemcitabine
Drug: Cisplatin

This study is an open-label, Phase 1, multicenter study to evaluate the safety, tolerability, PK, and PD profiles of AGEN2373 as a monotherapy and in...

Active, not recruiting
Advanced Cancer
Drug: Botensilimab
Drug: AGEN2373

This is a prospective, multi-center, randomized, controlled, patient- and evaluator-blinded study comparing treatment with the CardiAMP cell therapy...

Active, not recruiting
Heart Failure, Systolic
Other: Sham
Biological: Autologous cell therapy

CB010A is a study evaluating safety, emerging efficacy, pharmacokinetics and immunogenicity of CB-010 in adults with relapsed/refractory B cell non-H...

Enrolling
Refractory B-Cell Non-Hodgkin Lymphoma
B Cell Lymphoma
Drug: Cyclophosphamide
Genetic: CB-010

INDP-D101 is a Phase 1, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of De...

Enrolling
Solid Tumor, Adult
Drug: Decoy20

The objective of the study is to assess the safety and effectiveness of MiniMed™ 780G system in adult subjects with insulin-requiring type 2 diabetes...

Enrolling
Type 2 Diabetes Treated With Insulin
Device: MiniMed™ 780G Insulin Pump system

An open label, dose escalation and dose expansion study to evaluate the safety, tolerability, and anti-tumor activity of STP707 with IV administratio...

Active, not recruiting
Solid Tumor
Drug: STP707

The purpose of this study is to evaluate the long-term safety in patients with TSC and refractory seizures who are currently receiving everolimus tre...

Active, not recruiting
Tuberous Sclerosis Complex
Drug: everolimus

Prospective, interventional multicenter study evaluating adoptive cell therapy (ACT) via infusion of LN-144 (autologous TIL) followed by interleukin...

Active, not recruiting
Metastatic Melanoma
Biological: Lifileucel

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...

Enrolling
Microsatellite Instability
Mismatch Repair Deficiency
Biological: RP1
Biological: nivolumab

This study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that overexpress c-Met (c-Met+) best suited for teliso...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Telisotuzumab vedotin

Keynote 695 is Phase 2 study of intratumoral tavokinogene telseplasmid (tavo; pIL-12) Electroporation (EP) plus IV Pembrolizumab. Eligible patients w...

Active, not recruiting
Stage III/IV Melanoma
Biological: Pembrolizumab
Biological: tavokinogene telseplasmid

Trial conditions

Melanoma (9 trials)
Prolapse (7 trials)
Cancer (6 trials)
Pelvic Organ Prolapse (6 trials)
Carcinoma (5 trials)
Adenocarcinoma (4 trials)
COVID-19 (4 trials)
Urinary Incontinence (4 trials)
Leukemia (3 trials)
Non-Small-Cell Lung Carc... (3 trials)

And 67 more

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