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Atlantic Health System | Oncology Research

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Top treatments

CPI-613
Nivolumab
Trastuzumab
Ipilimumab
Carboplatin
Zanubrutinib
Gemcitabine
BGB-3111
BMS-986253
Lidocaine

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Active trials

20 of 66 total trials

7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

This is a Phase 4, U.S. only, multi-center study using a 7-day therapeutic response dose (TRD) of commercial Sucraid® to assess the response of treat...

Enrolling
CSID
Congenital Sucrase-Isomaltase Deficiency
Biological: Sucraid (sacrosidase) Oral Solution 8500 IU/mL

This Phase 3, multinational, single-arm study was designed to evaluate the efficacy and safety of UGN-102 as primary chemoablative therapy in patient...

Active, not recruiting
Bladder Cancer
Urothelial Carcinoma
Drug: UGN-102

The purpose of this study is to investigate experimental medication BMS-986253 in combination with Nivolumab or Nivolumab plus Ipilimumab in particip...

Active, not recruiting
Melanoma
Cancer
Biological: Ipilimumab
Other: Placebo

The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and...

Enrolling
Solid Tumors
Drug: Nivolumab
Drug: DF6002

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker pat...

Enrolling
Carcinoma, Non-Small-Cell Lung
Adenocarcinoma of Lung
Drug: Pemetrexed
Drug: Carboplatin

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of th...

Enrolling
Crohn's Disease
Drug: Mirikizumab

This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Venetoclax
Drug: Azacitidine

The main purpose of this study is to establish the safety and the recommended dose of TRK-950 in combination with FOLFIRI, Gemcitabine / Cisplatin, G...

Enrolling
Solid Tumor
Epithelial Ovarian Cancer
Drug: Pembrolizumab
Drug: Paclitaxel

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult...

Enrolling
Phenylketonurias
Genetic: NGGT002

This is a prospective, multi-center, randomized, controlled, patient- and evaluator-blinded study comparing treatment with the CardiAMP cell therapy...

Active, not recruiting
Heart Failure, Systolic
Biological: Autologous cell therapy
Other: Sham

This is a Phase I open label multi-center study to evaluate the safety, tolerability, pharmacokinetics and preliminary effectiveness of the investiga...

Enrolling
Advanced Non-Small Cell Squamous Lung Cancer
NSCLC Stage IV
Drug: MYTX-011

CB010A is a study evaluating safety, emerging efficacy, pharmacokinetics and immunogenicity of CB-010 in adults with relapsed/refractory B cell non-H...

Enrolling
Refractory B-Cell Non-Hodgkin Lymphoma
B Cell Lymphoma
Genetic: CB-010
Drug: Cyclophosphamide

INDP-D101 is a Phase 1, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of De...

Enrolling
Solid Tumor, Adult
Drug: Decoy20

The objective of the study is to assess the safety and effectiveness of MiniMed™ 780G system in adult subjects with insulin-requiring type 2 diabetes...

Active, not recruiting
Type 2 Diabetes Treated with Insulin
Device: MiniMed™ 780G Insulin Pump system

The purpose of this study is to evaluate the long-term safety of zanubrutinib regimens in participants with B-cell malignancies who participated in a...

Invitation-only
B-cell Malignancies
Drug: Zanubrutinib
Drug: Tislelizumab

An open label, dose escalation and dose expansion study to evaluate the safety, tolerability, and anti-tumor activity of STP707 with IV administratio...

Active, not recruiting
Solid Tumor
Drug: STP707

The purpose of this study is to evaluate the long-term safety in patients with TSC and refractory seizures who are currently receiving everolimus tre...

Active, not recruiting
Tuberous Sclerosis Complex
Drug: everolimus

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects...

Enrolling
Microsatellite Instability
Mismatch Repair Deficiency
Biological: RP1
Biological: nivolumab

This study is designed to identify the target Non-Small Cell Lung Cancer (NSCLC) population(s) that overexpress c-Met (c-Met+) best suited for teliso...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Telisotuzumab vedotin

Keynote 695 is Phase 2 study of intratumoral tavokinogene telseplasmid (tavo; pIL-12) Electroporation (EP) plus IV Pembrolizumab. Eligible patients w...

Active, not recruiting
Stage III/IV Melanoma
Biological: Pembrolizumab
Biological: tavokinogene telseplasmid

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