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Austin Neuromuscular Center | Austin, TX

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Active trials

13 of 28 total trials

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults with Multifocal Motor Neuropathy (ARDA+)

This trial is an extension of the antecedent trial ARGX-117-2002. It is a multicenter trial that has been designed to evaluate the long-term safety a...

Active, not recruiting
Multifocal Motor Neuropathy (MMN)
Other: Placebo
Biological: ARGX-117

The primary objective of this study is to evaluate the efficacy of tofersen in presymptomatic adult carriers of a superoxide dismutase 1 (SOD1) mutat...

Enrolling
Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation
Drug: Tofersen
Drug: Placebo

The purpose of this study is to measure the long-term safety and tolerability of efgartigimod PH20 SC in adult participants with IIM who previously p...

Invitation-only
Dermatomyositis
Myositis
Biological: EFG PH20 SC

A Phase II/III Randomized, Double-blind, Placebo-controlled, Multicenter Study to Determine the Efficacy and Safety of ABC008 in the Treatment of Sub...

Active, not recruiting
Inclusion Body Myositis
Drug: ABC008
Locations recently updated

This study's purpose is to measure the treatment response from efgartigimod PH20 SC compared with placebo in participants with Idiopathic Inflammator...

Enrolling
Dermatomyositis
Myositis
Biological: EFG PH20 SC
Other: PBO

This study is researching an experimental combination treatment with pozelimab and cemdisiran, and cemdisiran monotherapy. The study is focused on pa...

Enrolling
Generalized Myasthenia Gravis
Drug: Pozelimab
Drug: Pozelimab + Cemdisiran

To evaluate the efficacy of Pozelimab/Cemdisiran combination therapy in patients with sIBM

Enrolling
Idiopathic Inflammatory Myopathies
Sporadic Inclusion Body Myositis (sIBM)
Combination Product: Pozelimab/Cemdisiran

The main purpose of this study is to evaluate the safety and efficacy of nipocalimab compared to placebo in delaying relapse in adults with chronic i...

Enrolling
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Drug: Nipocalimab
Drug: Placebo

ABC008-IBM-202 is an open-label, multicenter study to evaluate the safety and efficacy of long-term administration of ulviprubart (ABC008) in subject...

Active, not recruiting
Inclusion Body Myositis (IBM)
Drug: Ulviprubart (ABC008)

A study of sevasemten (EDG-5506) in Becker muscular dystrophy (known as CANYON) and pivotal cohort (known as GRAND CANYON). The EDG-5506-201 CANYON s...

Enrolling
Becker Muscular Dystrophy
Drug: Placebo
Drug: Sevasemten 10 mg

The Phoenix Trial is a randomized double blind placebo controlled Phase III trial to evaluate the safety and efficacy of AMX0035 for treatment of ALS

Active, not recruiting
Amyotrophic Lateral Sclerosis
Other: Placebo
Drug: AMX0035

The purpose of this study is to evaluate the efficacy and safety of orally administered M5049 in idiopathic inflammatory myopathies, specifically der...

Enrolling
Dermatomyositis
Polymyositis
Drug: Placebo
Drug: M5049 high dose

This study will be comprised of 2 parts: 1) Part A (Multiple Ascending Dose \[MAD\]) will be conducted to evaluate the safety and tolerability of ves...

Active, not recruiting
Duchenne Muscular Dystrophy
Drug: Vesleteplirsen

Trial sponsors

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