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Biopharma Informatic | McAllen, TX

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LY3537031
Brenipatide
Tirzepatide
Vonoprazan
NNC0487-0111
Survodutide
Deudomperidone
Finerenone
Cilofexor
CIN-102

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Active trials

12 of 21 total trials

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in...

Enrolling
Metabolic Dysfunction-Associated Steatotic Liver Disease
Drug: Tirzepatide
Drug: Placebo

This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or He...

Enrolling
Obesity
Heart Failure
Drug: NNC0487-0111
Drug: Placebo

The primary objective of this study is to assess the efficacy of vonoprazan 20 mg once daily (QD) compared to placebo QD in the number of participant...

Active, not recruiting
Eosinophilic Esophagitis
Drug: Placebo
Drug: Vonoprazan

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in pa...

Enrolling
Irritable Bowel Syndrome
Constipation
Drug: LY3537031
Drug: Placebo

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated, what side effects may occur, and the safety and efficacy in p...

Enrolling
Irritable Bowel Syndrome
Diarrhea
Drug: LY3537031
Drug: Placebo

This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additiona...

Active, not recruiting
Overweight
Obesity
Drug: Placebo
Drug: Tirzepatide

The main purpose of this study is to look at how efgartigimod affects thyroid function in adults with Graves' Disease (GD). The study will also check...

Enrolling
Graves Disease
Graves' Disease
Biological: Efgartigimod PH20 SC
Other: Placebo PH20 SC

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to evaluate the efficacy of muvalaplin in reducing cardiovascular risk in participants with high lipoprotein(a) who have...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Placebo
Drug: Muvalaplin

The purpose of this clinical trial is to learn about the safety, pharmacokinetics (pharmacokinetics helps us understand how the drug is changed and e...

Enrolling
COVID-19
Drug: nirmatrelvir
Drug: ritonavir

This study is open to adults who are at least 18 years old and have:* A confirmed liver disease called non-alcoholic steatohepatitis (NASH) or* A con...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis
Combination Product: Survodutide
Combination Product: Placebo matching survodutide

This study is open to adults who are at least 18 years old living with obesity and have:* a confirmed liver disease called non-alcoholic steatohepati...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis (MASH)
Liver Fibrosis
Combination Product: Placebo
Combination Product: Survodutide

Trial sponsors

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