BRCR Medical Center | Plantation, FL

Research site
8200 W Sunrise Boulevard Suite D1 -D2, Plantation, Florida, United States of America
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17 of 28
Status: Active
Trial type: Interventional
Funder type: Industry

A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation

A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS G12C mutation to determine the maximum tolerated dose and recom...

Solid Tumor
Cancer of Pancreas
Drug: HBI-2438

A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS or EGFR mutations to determine the maximum tolerated dose and r...

Solid Tumor
Cancer of Colon
Drug: HBI-2376

The study is designed to evaluate the safety and efficacy of rusfertide in subjects with polycythemia vera (PV) in maintaining hematocrit control and...

Polycythemia Vera
Drug: Placebo
Drug: Rusfertide

This is a Phase 3 double-blind, placebo-controlled, randomized study designed to investigate whether tafasitamab and lenalidomide as an add-on to rit...

Active, not recruiting
Marginal Zone Lymphoma
Follicular Lymphoma
Drug: rituximab
Drug: placebo

The purpose of the study is to evaluate the overall survival of participants treated with imetelstat compared to best available therapy with intermed...

Drug: Imetelstat
Drug: Best Available Therapy (BAT)

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adu...

Crohn's Disease
Drug: Etrasimod
Drug: Placebo

The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of TTFields, using the NovoTTF-200T device, c...

Active, not recruiting
Nonsmall Cell Lung Cancer
Drug: Immune checkpoint inhibitors or docetaxel
Device: NovoTTF-200T

Brief Summary:The study is a prospective, randomized controlled phase III trial aimed to test the efficacy and safety of Tumor Treating Fields (TTFie...

Active, not recruiting
Pancreas Adenocarcinoma
Drug: Gemcitabine
Drug: nab paclitaxel

The goal of this clinical trial is to test ELVN-002 in people with cancers that have an abnormal HER2 gene. The main question the trial aims to answe...

HER2 Mutant Non-small Cell Lung Cancer
HER2 Amplification
Drug: ELVN-002
Drug: Trastuzumab emtansine

A Phase 1/2a Open-Label Dose Escalation and Dose Expansion Study of T3011 when Administered Intravenously as a Single Agent and in Combination with O...

Active, not recruiting
Endometrial Cancer
Solid Tumor
Biological: T3011

This is a multicenter, open-label, single-arm Phase II study to evaluate anti-tumor efficacy and safety of NT-I7 in combination with atezolizumab in...

Active, not recruiting
Non-Small Cell Lung Carcinoma
Nonsmall Cell Lung Cancer
Drug: efineptakin alfa
Drug: Atezolizumab
Recently updated

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Metastatic Cancer
Advanced Cancer
Drug: MRTX849
Drug: Afatinib

This study will compare the efficacy of the investigational agent sitravatinib in combination with nivolumab versus docetaxel in patients with advanc...

Active, not recruiting
Metastatic Non-Squamous Non-Small Cell Lung Cancer
Drug: Sitravatinib
Drug: Docetaxel

The study is a prospective, randomized controlled phase III trial, to test the efficacy, safety and neurocognitive outcomes of advanced NSCLC patient...

Active, not recruiting
Brain Metastases From Non-small Cell Lung Cancer (NSCLC)
Other: Best Standard of Care
Device: NovoTTF-200M device

This is a randomized, multicenter, Phase 3, open-label study evaluating subcutaneous (SC) vs intravenous (IV) administration of isatuximab in combina...

Plasma Cell Myeloma Recurrent
Drug: Pomalyst or equivalent
Drug: Isatuximab IV

The participants of this study would have relapsed/refractory follicular lymphoma.Follicular lymphoma is a type of blood cancer. It is referred to as...

Relapsed/Refractory Follicular Lymphoma
Follicular Lymphoma
Combination Product: Lenalidomide
Drug: Tazemetostat

The purpose of this study is to evaluate the efficacy and safety of imetelstat in transfusion-dependent participants with low or intermediate-1 risk...

Active, not recruiting
Myelodysplastic Syndromes
Drug: Imetelstat
Drug: Placebo

Trial conditions

Lung Cancer (7 trials)
Non-Small-Cell Lung Carc... (5 trials)
Colitis (3 trials)
Lymphoma (3 trials)
Ulcer (3 trials)
Ulcerative Colitis (3 trials)
Crohn Disease (2 trials)
Follicular Lymphoma (2 trials)
Myelodysplastic Syndromes (2 trials)
Neoplasm Metastasis (2 trials)

And 27 more

Clinical trials

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