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Canadian Phase Onward | Toronto, Canada

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Top conditions

Top treatments

Varenicline
Retatrutide
LY3437943
ACT-541468
Brenipatide
LY3537031
Aprocitentan
DDP733
BI 456906
Bococizumab

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Active trials

7 of 48 total trials
Locations recently updated

A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C) (RENEW-IBS-C)

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated what side effects may occur, and the safety and efficacy in pa...

Enrolling
Irritable Bowel Syndrome
Constipation
Drug: LY3537031
Drug: Placebo
Locations recently updated

The purpose of this study is to evaluate how well brenipatide (LY3537031) is tolerated, what side effects may occur, and the safety and efficacy in p...

Enrolling
Irritable Bowel Syndrome
Diarrhea
Drug: LY3537031
Drug: Placebo

The purpose of this study is to investigate the efficacy and safety of different retatrutide dose escalation schemes in participants without type 2 d...

Active, not recruiting
Overweight
Obesity
Drug: Retatrutide

This study is open to adults between 18 and 74 years of age and who have a body mass index (BMI) of 30 kg/m2 or more, or a BMI of 27 kg/m2 or more an...

Enrolling
Overweight
Obesity
Drug: Placebo matching BI 3034701
Drug: BI 3034701

The combination drug composed of aroxybutynin and atomoxetine, designated AD109, is being developed by Apnimed for the treatment of obstructive sleep...

Invitation-only
OSA
Drug: Aroxybutynin and Atomoxetine

The purpose of this study is to evaluate the safety and tolerability of olezarsen in participants with SHTG.

Active, not recruiting
Severe Hypertriglyceridemia
Drug: Olezarsen

Evaluation of safety, tolerability and efficacy of a single intra-articular (IA) injection of PTP-001, an allogeneic placental tissue particulate, in...

Active, not recruiting
Osteoarthritis, Knee
Biological: PTP-001
Other: Placebo control

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