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Cardiovascular Research Institute of Kansas, LLC | Wichita, KS

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Active trials

15 of 17 total trials

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects who are...

Enrolling
Aortic Valve Stenosis
Aortic Valve Insufficiency
Device: SAPIEN X4 THV

The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valv...

Enrolling
Atrial Fibrillation
Stroke
Drug: Non-Vitamin K Oral Antagonists
Device: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder)

The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN®...

Active, not recruiting
Stroke
Device: WATCHMAN Left Atrial Appendage Closure
Device: Amulet Left Atrial Appendage Occluder

Prospective, controlled, multicenter clinical investigation with four trial cohorts: Randomized, Non-repairable, Severe Mitral Annular Calcification...

Enrolling
Heart Valve Diseases
Degenerative Mitral Valve Disease
Device: Tendyne Mitral Valve System
Device: MitraClip System

Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated he...

Enrolling
ADHF
Heart Failure, Diastolic
Device: Aortix System

This study will evaluate the safety and effectiveness of the Edwards SAPIEN 3/SAPIEN 3 Ultra Transcatheter Heart Valve (THV) compared with clinical s...

Active, not recruiting
Aortic Stenosis, Severe
Heart Diseases
Device: Edwards SAPIEN 3 / SAPIEN 3 Ultra THV

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation...

Enrolling
Degenerative Mitral Valve Disease
Functional Mitral Regurgitation
Device: Edwards PASCAL System
Device: Abbott Mitraclip System
Locations recently updated

To demonstrate the safety and effectiveness of the Reducer system for treatment of patients with refractory angina pectoris treated with maximally to...

Enrolling
Refractory Angina
Other: Arm 2 (control): Implantation procedure with no device implanted
Device: Arm 3 (unblinded, non-randomized): Single arm registry

The study is an early feasibility study to measure individual patient clinical outcomes and effectiveness, evaluate the safety and function of the DU...

Enrolling
Heart Valve Diseases
Tricuspid Valve Insufficiency
Device: DUO Transcatheter Tricuspid Coaptation Valve System

The objective of ENVISION is to evaluate the safety and effectiveness of the Navitor Transcatheter Aortic Valve Implantation (TAVI) System for treati...

Enrolling
Heart Valve Diseases
Aortic Valve Stenosis
Device: Navitor Transcatheter Aortic Valve Implantation (TAVI) System
Device: Any Commercially Available Transcatheter Aortic Valve (CAV) System

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided hea...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump

The purpose of this clinical study is to evaluate the acute safety and effectiveness of the next-generation Navitor (Portico™ NG) Transcatheter Aorti...

Active, not recruiting
Symptomatic Severe Aortic Stenosis
Device: Portico™ NG (Navitor) Valve and FlexNav™ Delivery System
Device: Navitor Titan Valve (35mm) Valve and Large FlexNav™ Delivery System

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Hea...

Enrolling
Aortic Valve Stenosis
Aortic Stenosis, Calcific
Device: SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA

Prospective, multi-center, randomized, single blind, controlled, noninferiority clinical trial.Subjects with previous bare-metal stent (BMS) or DES a...

Enrolling
Coronary Restenosis
Device: SELUTION SLR™ DEB
Device: Control

The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in t...

Enrolling
Heart Valve Diseases
Mitral Valve Insufficiency
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System

Trial sponsors

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