Lovosice, Czech Republic

CEFISPIRO s.r.o.

Chronic Obstructive Pulmonary Disease

Lung Diseases

Obstructive Lung Diseases

Dyspnea

Bronchitis

Respiratory Tract Diseases

Respiratory Sounds

Airway Obstruction

Chronic Bronchitis

Asthma

ION-827359

Ensifentrine

PF-07275315

Ionis Pharmaceuticals

Pfizer

Verona Pharma

condition

Respiratory Hypersensitivity

allSponsorName

gender

Male

Female

overallStatus

Recruiting

Not yet recruiting

Active, not recruiting

Enrolling by invitation

Completed

Terminated

Withdrawn

Suspended

Unknown

type

Interventional

Observational

Expanded Access

phase

Early Phase 1

Phase 1

Phase 2

Phase 3

Phase 4

Not Applicable

funderTypes

Industry

Other U.S. Federal agency

All others

ageGroup

Child (birth-17)

Adult (18-64)

Older Adult (65+)

The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-07275315) for the potential treatment of moderate-to-severe asthma. Asthma is a condition that makes it challenging to breathe, which negatively impacts the quality of life and functioning of people who are affected.

This study is seeking participants who:

* Are 18 to 70 years old
* Have had moderate-to-severe asthma for at least 12 months that is not well controlled
* Have been taking their regular maintenance treatment(s) for asthma over the last 12 months

All participants will receive PF-07275315 or a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied.

PF-07275315 or placebo will be given as multiple shots in the clinic over the course of 12 weeks. We will compare the experiences of people receiving PF-07275315 to those of the people who do not. This will help us determine if PF-07275315 is safe and effective.

Participants will be involved in this study for about 7.5 months. During this time, they will have 9 visits at the study clinic.

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

CEFISPIRO s.r.o. | Lovosice, Czech Republic

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A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma

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