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Data sourced from clinicaltrials.gov

Active trials

9 of 202 total trials

A Drug-Drug Interaction Study of Denifanstat and Resmetirom in Healthy Adult Participants

This is an open-label, 2-cohort study to evaluate the mutual DDI potential between denifanstat and resmetirom in healthy adult participants.

Active, not recruiting
Healthy
Drug: Resmetirom
Drug: Denifanstat

This is a study to determine the safety of CDX-622 in healthy participants.

Enrolling
Healthy Participants
Drug: Normal Saline
Drug: CDX-622

The main objective of the study is to assess the relative bioavailability of KAI-9531 subcutaneous (SC) injection in the upper arm and thigh compared...

Active, not recruiting
Healthy Volunteers
Drug: KAI-9531

The purposes of this Phase 1 study of EDG-15400 are to:1. Learn about the safety of EDG-15400 after single and multiple doses in healthy adults2. Lea...

Enrolling
Healthy Adults
Drug: EDG-15400
Drug: Placebo

The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics of BMS-986419 (Part 1) and the effects of multiple doses o...

Enrolling
Healthy Volunteers
Drug: Moxifloxacin Matching Placebo
Drug: Moxifloxacin

The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in he...

Active, not recruiting
Healthy Participants
Drug: Casdatifan
Drug: Phenytoin

A Phase 2a study of PORT-77 in adults with erythropoietic protoporphyria (EPP)

Invitation-only
Erythropoietic Protoporphyria (EPP)
Drug: PORT-77
Drug: Placebo

This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the saf...

Enrolling
Acne
Drug: Placebo
Drug: TVB-3567

A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation...

Enrolling
Healthy Adult Participants
Drug: Placebo
Drug: PORT-77

Trial sponsors

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Merck Sharp & Dohme (MSD) logo
Janssen (J&J Innovative Medicine) logo
Vertex Pharmaceuticals logo
Lilly logo
C
Acerta Pharma logo
C
Corcept Therapeutics logo
Incyte logo

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