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Data sourced from clinicaltrials.gov

Active trials

18 of 193 total trials

A Cardiac Liability Study of Varegacestat in Healthy Participants

This clinical study is designed to study the effect of a single dose of varegacestat on cardiac repolarization in healthy adult participants.

Active, not recruiting
Healthy Volunteer
Drug: Moxifloxacin 400 mg
Drug: Placebo

Researchers designed belzutifan, the study medicine, to treat certain kinds of cancer.The goal of this study is to learn what happens to belzutifan i...

Active, not recruiting
Healthy
Drug: Belzutifan
Drug: Phenytoin

The goal of the study is to learn what happens to different forms of enlicitide medications in a healthy person's body over time. Researchers will co...

Enrolling
Healthy
Drug: Enlicitide

Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer.The purpose of this study is to learn what happen...

Active, not recruiting
Healthy
Drug: Carbamazepine
Drug: Opevesostat

This study is the first study with TAK-004 conducted in human beings. Participants will receive either TAK-004 or placebo. The main aim of this study...

Enrolling
Healthy Volunteers
Drug: Placebo
Drug: TAK-004

The purpose of this study is to evaluate the relative bioavailability of a VX-828 tablet formulation compared to a suspension and evaluate its safety...

Active, not recruiting
Cystic Fibrosis
Drug: VX-828

This is a study to determine the safety of CDX-622 in healthy participants.

Enrolling
Healthy Participants
Drug: Normal Saline
Drug: CDX-622

The goal of this study is to learn what happens to MK-8527 in a healthy person's body over time when MK-8527 is given alone and with the medication C...

Enrolling
Healthy
Drug: MK-8527
Drug: CBZ

The main aim of this study is to understand how the body absorbs, processes, and removes (known as pharmacokinetics or PK) TAK-881 and HyQvia, after...

Enrolling
Healthy Volunteers
Biological: TAK-881
Biological: HyQvia

The main aim of this study is to check how well healthy adults can tolerate TAK-881 with different dosing schedules.During the study, participants wi...

Enrolling
Healthy Volunteers
Biological: TAK-881
Device: SC Investigational Needle Sets

This study will be conducted to evaluate a Single-Dose Subcutaneous (SC) Axatilimab Compared With Intravenous Axatilimab in Healthy Participants.

Enrolling
Healthy Participants
Drug: Axatilimab

This study has 2 parts. Researchers want to learn what happens to MK-1084 in a healthy person's body over time in both parts. The goals of the study...

Enrolling
Healthy
Drug: MK-1084 FCT
Drug: MK-1084 OCT

The purpose of this study is to evaluate the Relative Bioavailability of New Formulations of INCB057643 Tablets Administered Orally in Healthy Partic...

Enrolling
Healthy Volunteers
Drug: INCB057643

The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics of BMS-986419 (Part 1) and the effects of multiple doses o...

Enrolling
Healthy Volunteers
Drug: Moxifloxacin Matching Placebo
Drug: Moxifloxacin

The purpose of the study is to assess the effects of multiple doses of itraconazole (a strong CYP3A4 inhibitor) on single dose PK of casdatifan in he...

Enrolling
Healthy Participants
Drug: Casdatifan
Drug: Phenytoin

The purpose of this study is to evaluate the effect of SUZ on the pharmacokinetics of oral contraceptives.

Active, not recruiting
Pain
Drug: DRSP/EE
Drug: NGM/EE

A Phase 2a study of PORT-77 in adults with erythropoietic protoporphyria (EPP)

Invitation-only
Erythropoietic Protoporphyria (EPP)
Drug: PORT-77
Drug: Placebo

A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation...

Enrolling
Healthy Adult Participants
Drug: Placebo
Drug: PORT-77

Trial sponsors

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Janssen (J&J Innovative Medicine) logo
Merck Sharp & Dohme (MSD) logo
Vertex Pharmaceuticals logo
Lilly logo
C
Acerta Pharma logo
C
Corcept Therapeutics logo
Incyte logo

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