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Data sourced from clinicaltrials.gov

Active trials

7 of 170 total trials

A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg

This study investigates the safety, tolerability and dose equivalence of drug IkT-001Pro in healthy volunteers (18 to 55 years old) in comparison to...

Active, not recruiting
CML
Drug: IkT-001Pro
Drug: Imatinib Mesylate

The purposes of this study are to:* Learn about the safety and tolerability of CK 4021586 after a single dose and multiple doses in healthy subjects....

Enrolling
Healthy Participants
Drug: CK-4021586
Drug: Placebo for CK-4021586

The goal of the study is to see what happens to levels of midazolam and digoxin in a person's body over time (a pharmacokinetic or PK study). Researc...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Digoxin
Drug: MK-1084
Recently updated

This study is conducted to determine the Bioequivalence of Ruxolitinib XR 55 mg Tablets With Ruxolitinib IR Tablets Administered Orally in Healthy Pa...

Enrolling
Healthy Participants
Drug: Ruxolitinib XR
Drug: Ruxolitinib IR

Researchers have designed a study medicine called bomedemstat (MK-3543) as a new way to treat certain rare blood diseases.The purpose of this study i...

Enrolling
Healthy
Drug: bomedemstat
Drug: carbamazepine

A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation...

Not yet enrolling
Healthy Adult Participants
Drug: Placebo
Drug: PORT-77

This study in healthy volunteers will provide a basis for evaluation of TRL345 as a first in human study, specifically, important safety, tolerabilit...

Enrolling
Healthy Volunteers
Drug: TRL345, a human monoclonal antibody

Trial sponsors

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Merck Sharp & Dohme (MSD) logo

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