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Itraconazole
Selpercatinib
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TAK-279
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Data sourced from clinicaltrials.gov

Active trials

11 of 180 total trials
Status recently updated

A Cardiac Liability Study of Varegacestat in Healthy Participants

This clinical study is designed to study the effect of a single dose of varegacestat on cardiac repolarization in healthy adult participants.

Begins enrollment in 1 month
Enrolling
Healthy Volunteer
Drug: Moxifloxacin 400 mg
Drug: Placebo

Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer.The purpose of this study is to learn what happen...

Active, not recruiting
Healthy
Drug: Carbamazepine
Drug: Opevesostat

This study is the first study with TAK-004 conducted in human beings. Participants will receive either TAK-004 or placebo. The main aim of this study...

Enrolling
Healthy Volunteers
Drug: Placebo
Drug: TAK-004

This is an open label, fixed sequence, 1-way crossover drug-drug interaction (DDI) study in healthy participants.

Active, not recruiting
Healthy Volunteer
Drug: Itraconazole (200 mg)
Drug: varegacestat

This is a study to determine the safety of CDX-622 in healthy participants.

Enrolling
Healthy Participants
Drug: Normal Saline
Drug: CDX-622

The purposes of this study are to:* Learn about the safety and tolerability of CK 4021586 after a single dose and multiple doses in healthy subjects....

Enrolling
Healthy Participants
Drug: CK-4021586
Drug: Placebo for CK-4021586

The main aim of this study is to find out how zasocitinib (TAK-279) interacts with other medicines taken by mouth (orally). This will be examined by...

Enrolling
Healthy Volunteers
Drug: Esomeprazole
Drug: Digoxin

This study will be conducted to evaluate a Single-Dose Subcutaneous (SC) Axatilimab Compared With Intravenous Axatilimab in Healthy Participants.

Enrolling
Healthy Participants
Drug: Axatilimab

Researchers have designed a study medicine called bomedemstat (MK-3543) as a new way to treat certain rare blood diseases.The purpose of this study i...

Active, not recruiting
Healthy
Drug: bomedemstat
Drug: carbamazepine

A First-in-Human 2-part, randomized, double-blind, placebo-controlled, single ascending dose, multiple ascending dose, and food effect, investigation...

Enrolling
Healthy Adult Participants
Drug: Placebo
Drug: PORT-77

This study in healthy volunteers will provide a basis for evaluation of TRL345 as a first in human study, specifically, important safety, tolerabilit...

Active, not recruiting
Healthy Volunteers
Drug: TRL345, a human monoclonal antibody

Trial sponsors

Takeda logo
Janssen (J&J Innovative Medicine) logo
Merck Sharp & Dohme (MSD) logo
Lilly logo
Vertex Pharmaceuticals logo
C
Acerta Pharma logo
C
Corcept Therapeutics logo
Madrigal Pharmaceuticals logo

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