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14 of 196
Status: Active
Trial type: Interventional
Funder type: Industry

A Study Evaluating Rocatinlimab in Moderate-to-severe Atopic Dermatitis (ROCKET-IGNITE) (ROCKET-Ignite)

The purpose of this study is to evaluate the efficacy and safety of rocatinlimab in monotherapy treatment.

Atopic Dermatitis
Drug: Rocatinlimab
Drug: Placebo

The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...

Active, not recruiting
Biological: mRNA-1273.222
Biological: mRNA-1283.222

This study is to evaluate the Pharmacodynamic (PD), safety, tolerability, Pharmacokinetic (PK), and plasma biomarker response of KAN-101 in participa...

Celiac Disease
Drug: Cohort 2 in Part A
Drug: Group 4 in Part B and Part C

The objective of this study is to assess the bioavailability of risankizumab liquid vial manufactured with the new process (CMC3) relative to the cur...

Active, not recruiting
Healthy Volunteers
Drug: Risankizumab

The purpose of this study is to assess the safety, tolerability, and single-dose pharmacokinetics of danicamtiv in healthy Japanese and Caucasian par...

Healthy Volunteers
Drug: Placebo
Drug: Danicamtiv

The purpose of the study is to learn about the safety of PF-07817883 and how PF-07817883 is processed in the body of adult participants. These partic...

Drug: PF-07817883

The purpose of the study is to learn how the study medicine called PF-07868489 is tolerated and acts in healthy adult people and people with pulmonar...

Pulmonary Arterial Hypertension
Drug: Placebo for PF-07868489
Drug: PF-07868489
Locations recently updated

The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple escalating oral doses o...

Type 2 Diabetes Mellitus (T2DM)
Drug: Placebo
Drug: Midazolam

The purpose of this study is to compare two finished products of PF-07940367 in terms of the uptake into the blood stream.This study is seeking parti...

Drug: PF-07940367

The primary objective of this study is to evaluate the analgesic efficacy of DMTS, compared with placebo, in subjects following abdominoplasty.

Pain, Postoperative
Drug: Placebo Patch
Drug: DMTS Patch

This study will evaluate safety, tolerability, pharmacokinetic (PK) profile, and pharmacodynamic (PD) effects on GSBR-1290 in healthy overweight/obes...

Active, not recruiting
Overweight or Obesity
Type2 Diabetes Mellitus
Drug: GSBR-1290
Drug: Placebo

The main objective of this study is to assess pharmacokinetics, safety, and tolerability of ABBV-932 in healthy adult participants.

Healthy Participants
Generalized Anxiety Disorder (GAD)
Drug: Placebo
Drug: ABBV-932

The purpose of the study is to learn how different forms of a study medication called danuglipron are taken into the blood in healthy adults.

Healthy Participants
Healthy Subjects
Drug: Formulation C
Drug: Formulation B

An antibody is a substance your body makes to fight off infection. This study will explore the safety and antibody response of a vaccine to prevent s...

Active, not recruiting
Clostridoides Difficile Associated Disease
Biological: C. difficile vaccine formulation 1.
Biological: C. difficile vaccine formulation 2.

Trial conditions

Psoriasis (17 trials)
Diabetes Mellitus (16 trials)
Type 2 Diabetes Mellitus (16 trials)
Postoperative Pain (12 trials)
Obesity (11 trials)
COVID-19 (8 trials)
Human Influenza (7 trials)
Acute Pain (6 trials)
Migraine Disorders (6 trials)
Colitis (5 trials)

And 62 more

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