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9 of 42
Status: Active
Trial type: Interventional
Funder type: Industry

A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication

A clinical study that will evalute how well SEP-363856 works and how safe it is in people with schizophrenia that switch to SEP-363856 from their cur...

Active, not recruiting
Drug: SEP-363856

The purpose of this study is to evaluate the efficacy of aticaprant compared with placebo as adjunctive therapy to an antidepressant in improving dep...

Depressive Disorder, Major
Other: Placebo
Drug: Aticaprant

The purpose of this study is to assess the long-term safety and tolerability of aticaprant administered as adjunctive therapy to a current antidepres...

Depressive Disorder, Major
Drug: Aticaprant

An Extension study to a clinical study that will continue to evaluate the effectiveness and safety of SEP-363856 in people with schizophrenia that sw...

Drug: SEP-363856

This is a Phase 3, multicenter, 56-week, outpatient, open-label (OL) study to evaluate the long-term safety, tolerability, and efficacy of KarXT in d...

Active, not recruiting
Drug: Xanomeline and Trospium Chloride Capsules

The study's purpose is to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compul...

Obsessive-Compulsive Disorder
Drug: Placebo
Drug: Troriluzole

Efficacy, Safety, and Tolerability of a single administration of COMP360 in participants with treatment-resistant depression (TRD)

Treatment Resistant Depression
Drug: Psilocybin

The purpose of the study is to evaluate the long term safety and tolerability of troriluzole as adjunctive therapy in subjects with obsessive compuls...

Obsessive Compulsive Disorder
Drug: Troriluzole (BHV-4157)

NMDA antagonist drugs have shown to reduce symptoms of depression and suicidal ideation. NeuroRx has developed NRX-101 (fixed dose combination of D-c...

Active, not recruiting
Suicidal Ideation and Behavior
Bipolar Depression
Drug: Lurasidone HCl
Drug: NRX-101

Trial conditions

Schizophrenia (22 trials)
Depression (14 trials)
Depressive Disorder (14 trials)
Major Depressive Disorder (10 trials)
Treatment-Resistant Depr... (4 trials)
Psychotic Disorders (3 trials)
Suicidal Ideation (3 trials)
Bipolar Disorder (2 trials)
Cognitive Dysfunction (2 trials)
Compulsive Personality D... (2 trials)

And 8 more

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