Centre for Human Drug Research | Leiden, Netherlands

Research site

(Unclaimed)

Location

Zernikedreef 8, Leiden, Zuid-Holland, Netherlands

Site insights

Top conditions

Top treatments

ACT-541468

DNL151

IW-6463

DNL343

Clindamycin

Erythromycin

POLB 001

Pregabalin

JNJ-42847922

QRL-101

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Data sourced from clinicaltrials.gov

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Active trials

8 of 70 total trials

A 3-way Cross-over Study on the Effects of QRL-101 on Transcranial Magnetic Stimulation and Nerve Excitability in Healthy Participants

This is a phase I, prospective, single-center, randomized, double-blind, placebo-controlled, three-way cross-over study to evaluate the safety and to...

Enrolling

Healthy

Drug: Placebo

Drug: QRL-101 Dose A

A Research Study Looking at the Safety of Single Doses of ZP9830 and How it Works in the Body of Healthy Participants

The primary object in this research study is to investigate the safety and tolerability of ZP9830 in healthy study participants, and in addition, the...

Enrolling

Autoimmune Diseases

Drug: Placebo

Drug: ZP9830

A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec

In this study, researchers will learn about a study drug called BIIB115 in healthy male volunteers and in participants with spinal muscular atrophy (...

Enrolling

Muscular Atrophy, Spinal

Healthy Volunteer

Drug: BIIB115-Matching Placebo

Drug: BIIB115

Anti-inflammatory Effects of Topical Erythromycin and Clindamycin in Acne Patients

The combined bacteriostatic and immunomodulatory effects of erythromycin and clindamycin will be explored. Treatment effects will be extensively char...

Enrolling

Acne Vulgaris

Drug: 70% topical ethanol solution

Drug: Clindamycin 1% topical lotion formulation

Phase 1/2 Study of AOC 1020 in Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

A Randomized, Double-blind, Placebo-controlled, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Explora...

Enrolling

Muscular Dystrophy, Landouzy Dejerine

Fascioscapulohumeral Muscular Dystrophy

Drug: Placebo

Drug: AOC 1020

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria (CALM-CSU)

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects with Chronic Spontaneous Urtica...

Enrolling

Chronic Spontaneous Urticaria

Drug: Placebo

Drug: Oral EP262

Single and Repeat Doses of DMT in Healthy Subjects

This study aims to assess the safety and tolerability of single ascending, and fixed repeated doses of N,N-Dimethyltryptamine (DMT) in healthy subjec...

Active, not recruiting

Stroke

Drug: Placebo

Drug: N,N-Dimethyltryptamine

Single Ascending Dose Study of MSD-001 in Healthy Participants

The purpose of this Phase 1 single ascending dose (SAD) study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamic profi...

Enrolling

Mental Health Disorders

Drug: Placebo Comparator

Drug: MSD-001