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Centre for Human Drug Research | Leiden, Netherlands

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ACT-541468
DNL151
IW-6463
DNL343
Clindamycin
Erythromycin
POLB 001
Pregabalin
JNJ-42847922
QRL-101

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Active trials

8 of 70 total trials

A 3-way Cross-over Study on the Effects of QRL-101 on Transcranial Magnetic Stimulation and Nerve Excitability in Healthy Participants

This is a phase I, prospective, single-center, randomized, double-blind, placebo-controlled, three-way cross-over study to evaluate the safety and to...

Enrolling
Healthy
Drug: Placebo
Drug: QRL-101 Dose A

The primary object in this research study is to investigate the safety and tolerability of ZP9830 in healthy study participants, and in addition, the...

Enrolling
Autoimmune Diseases
Drug: Placebo
Drug: ZP9830

In this study, researchers will learn about a study drug called BIIB115 in healthy male volunteers and in participants with spinal muscular atrophy (...

Enrolling
Muscular Atrophy, Spinal
Healthy Volunteer
Drug: BIIB115-Matching Placebo
Drug: BIIB115

The combined bacteriostatic and immunomodulatory effects of erythromycin and clindamycin will be explored. Treatment effects will be extensively char...

Enrolling
Acne Vulgaris
Drug: 70% topical ethanol solution
Drug: Clindamycin 1% topical lotion formulation

A Randomized, Double-blind, Placebo-controlled, Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Explora...

Enrolling
Muscular Dystrophy, Landouzy Dejerine
Fascioscapulohumeral Muscular Dystrophy
Drug: Placebo
Drug: AOC 1020

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects with Chronic Spontaneous Urtica...

Enrolling
Chronic Spontaneous Urticaria
Drug: Placebo
Drug: Oral EP262

This study aims to assess the safety and tolerability of single ascending, and fixed repeated doses of N,N-Dimethyltryptamine (DMT) in healthy subjec...

Active, not recruiting
Stroke
Drug: Placebo
Drug: N,N-Dimethyltryptamine

The purpose of this Phase 1 single ascending dose (SAD) study is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamic profi...

Enrolling
Mental Health Disorders
Drug: Placebo Comparator
Drug: MSD-001

Trial sponsors

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