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Centro Regional Integrado de Oncologia | Fortaleza, Brazil

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Pembrolizumab
Platinum
Ipilimumab
INCMGA00012
Pertuzumab
Paclitaxel
Capecitabine
Carboplatin
Lapatinib
Leuprolide Acetate

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Active trials

8 of 16 total trials
Locations recently updated

A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer (HER2CLIMB-05)

This study is being done to see if tucatinib works better than placebo when given with other drugs to treat participants with HER2-positive breast ca...

Active, not recruiting
HER2 Positive Breast Cancer
Drug: Pertuzumab
Drug: Trastuzumab

This trial will evaluate the safety and efficacy of pembrolizumab (MK-3475) in combination with platinum doublet neoadjuvant chemotherapy (NAC) befor...

Active, not recruiting
Non-small Cell Lung Cancer
Drug: Placebo
Drug: Pemetrexed

The purpose of this study is to characterize the safety, tolerability, PK, and efficacy of INCB 99280 in combination with ipilimumab in participants...

Active, not recruiting
Melanoma
Renal Cell Carcinoma (RCC)
Drug: INCB 99280 with Ipilimumab

A Phase III, randomised, double-blind, placebo-controlled, multi-centre study to assess the efficacy of olaparib maintenance monotherapy in relapsed...

Active, not recruiting
Relapsed Ovarian Cancer
Following Complete or Partial Response to Platinum Based Chemotherapy
Drug: Placebo to match olaparib 300mg
Drug: Olaparib 300mg tablets
Locations recently updated

This is a phase 3, single arm, open-label study evaluating the effectiveness of TOL2506 to suppress ovarian function in premenopausal women with HR+,...

Enrolling
Breast Cancer
Drug: Anastrozole Tablets
Drug: Tamoxifen

The purpose of this study is to assess the efficacy and safety of platinum-based chemotherapy with or without INCMGA00012 in participants with metast...

Active, not recruiting
Metastatic Nonsquamous Non-Small Cell Lung Cancer
Metastatic Squamous Non-Small Cell Lung Cancer
Drug: Placebo
Drug: Paclitaxel

The purpose of this study is to determine the efficacy and safety of pembrolizumab given concomitantly with chemoradiation (CRT) and as maintenance t...

Active, not recruiting
Head and Neck Neoplasms
Radiation: Standard Fractionation (SFX) Radiotherapy
Biological: Pembrolizumab

This is a randomized, active-controlled, open-label study of pembrolizumab (Pembro) given prior to surgery and pembrolizumab in combination with stan...

Active, not recruiting
Head and Neck Neoplasms
Radiation: Radiotherapy 70 Gray/day
Biological: Pembrolizumab 200 mg

Trial sponsors

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