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ARO-APOC3
AMT-101
Risankizumab
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Active trials

7 of 16 total trials

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease (GRAVITI)

The purpose of this study is to evaluate the efficacy and safety of guselkumab in participants with Crohn's disease.

Active, not recruiting
Crohn Disease
Drug: Guselkumab Dose 3
Drug: Placebo

This study will evaluate the efficacy and safety of ocrelizumab (Ocrevus®) compared with placebo in participants with primary progressive multiple sc...

Active, not recruiting
Multiple Sclerosis, Primary Progressive
Drug: Ocrelizumab
Drug: Placebo

This is a phase 3, randomized, placebo-controlled study of the efficacy and safety of enlicitide decanoate, an oral proprotein convertase subtilisin/...

Active, not recruiting
Arteriosclerosis
Hypercholesterolaemia
Drug: Placebo
Drug: Enlicitide Decanoate
Locations recently updated

A Phase 1 Dose Escalation and Expanded Cohort Study Of PF-06821497 (Mevrometostat) in Adult Patients With Relapsed/Refractory Small Cell Lung Cancer...

Enrolling
Follicular Lymphoma (FL)
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Drug: Enzalutamide
Drug: Mervometostat (PF-06821497)
Locations recently updated

This is an open-label extension of the parent studies AROAPOC3-2001 and AROAPOC3-2002. Adult participants with dyslipidemia who completed the blinded...

Active, not recruiting
Dyslipidemias
Drug: ARO-APOC3

Randomized, Placebo-controlled, Double-blind, Parallel-group, Multicenter, Phase 2a Study of the Efficacy and Safety of Oral AMT-101 in Subjects with...

Active, not recruiting
Ulcerative Colitis
Other: Placebo (oral)
Drug: AMT-101 (oral)

Transmural healing (TMH) is recognized as a potentially important measure of Crohn's disease (CD) activity but not a formal target. Observational stu...

Enrolling
Disease Crohn
Crohn Disease
Biological: Vedolizumab

Trial sponsors

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