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Charité Universitätsmedizin Berlin | Institute of Allergology (IFA) - Campus Benjamin Franklin logo

Charité Universitätsmedizin Berlin | Institute of Allergology (IFA) - Campus Benjamin Franklin

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Top conditions

Top treatments

CDX-0159
STAR-0215
BLU-263
CGT9486
LOU064
PHA-022121
EP262
THB001
Briquilimab
Remibrutinib

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This site is a part of Charité Universitätsmedizin Berlin

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Active trials

14 of 15 total trials

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

This is a randomized, double-blind, placebo-controlled, Phase 2/3 study comparing the efficacy and safety of elenestinib (BLU-263) + best supportive...

Enrolling
Monoclonal Mast Cell Activation Syndrome
Smoldering Systemic Mastocytosis
Drug: Placebo
Drug: Elenestinib

This is a multi-part, randomized, double-blind, placebo-controlled Phase 2 clinical study comparing the safety and efficacy of bezuclastinib (CGT9486...

Enrolling
Mastocytosis
Mastocytosis, Systemic
Drug: Bezuclastinib Tablets (Formulation A)
Drug: Placebo Tablets

The purpose of this trial is:1. to assess the efficacy, pharmacokinetics, and safety of remibrutinib vs. placebo in adolescents from 12 to \< 18 year...

Enrolling
Chronic Spontaneous Urticaria
Drug: placebo
Drug: LOU064 (blinded)

The goal of this trial is to enable the collection of information about long-term safety and clinical activity of STAR-0215 in participants with here...

Enrolling
Hereditary Angioedema
Drug: STAR-0215

The purpose of this study is to assess the clinical effect, the pharmacodynamics, the safety, and the pharmacokinetics of barzolvolimab (CDX-0159) in...

Active, not recruiting
Chronic Spontaneous Urticaria
Biological: barzolvolimab
Drug: Matching Placebo

The purpose of this study is to assess the clinical effect, the pharmacodynamics, the safety, and the pharmacokinetics of barzolvolimab (CDX-0159) in...

Active, not recruiting
Chronic Inducible Urticaria
Drug: Matching Placebo
Biological: barzolvolimab

The goal of this clinical trial is to test the drug STAR-0215 in participants with hereditary angioedema (HAE). One group of participants will get 1...

Active, not recruiting
Hereditary Angioedema
Drug: STAR-0215

The purpose of this extension study is to collect long-term efficacy, safety and tolerability data on remibrutinib in a selected group of participant...

Active, not recruiting
Chronic Spontaneous Urticaria
Drug: LOU064 (blinded)
Drug: Placebo

The purpose of this study is to investigate the safety, PK / PD, and efficacy of SC CSL312 for prophylactic treatment of pediatric subjects with HAE.

Enrolling
Hereditary Angioedema (HAE)
Biological: CSL312

This trial will be performed as a three-part dose escalating clinical trial where Parts 1 is open label and Parts 2 and 3 are randomized, double-blin...

Enrolling
Chronic Spontaneous Urticaria
Drug: Briquilimab
Other: Placebo

This study evaluates the safety and efficacy of long-term on-demand treatment with orally administered deucrictibant for acute hereditary angioedema...

Invitation-only
Hereditary Angioedema - Type 2
Hereditary Angioedema Types I and II
Drug: deucrictibant selected dose

This phase 1b trial will evaluate the effects of EP262 in subjects with Chronic Inducible Urticaria (CIndU), including symptomatic dermographism and...

Active, not recruiting
Chronic Inducible Urticaria
Drug: Oral EP262

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects with Chronic Spontaneous Urtica...

Enrolling
Chronic Spontaneous Urticaria
Drug: Placebo
Drug: Oral EP262

This is a multicenter pharmacokinetic (PK) subtrial to investigate the PK profile of KVD900 in adolescent patients 12 to 17 years of age with Heredit...

Enrolling
Hereditary Angioedema
Drug: KVD900 600 mg

Trial sponsors

A
Celldex Therapeutics logo
E
Novartis logo
B
CSL Behring logo
C
J
KalVista Pharmaceuticals logo
P

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