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Active trials

8 of 63 total trials

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (TRANSFORM)

TRANSFORM is a prospective, randomized, open blinded endpoint (PROBE), event-driven, pragmatic trial in patients who are at increased risk for athero...

Enrolling
Diabetes Mellitus, Type 2
Metabolic Syndrome
Device: The Cleerly CAD Staging System

This is a Phase 3, open-label, randomized trial designed to evaluate the RFS of TURBT followed by cretostimogene grenadenorepvec versus TURBT followe...

Enrolling
Bladder Cancer
Urologic Cancer
Other: n-dodecyl-B-D-maltoside
Drug: Cretostimogene Grenadenorepvec

Prospective, randomized, open-label, international, multi-center clinical study to evaluate the safety and efficacy of the AccuCinch Ventricular Rest...

Enrolling
Dilated Cardiomyopathy
Heart Failure With Reduced Ejection Fraction (HFrEF)
Device: AccuCinch Ventricular Restoration System
Drug: Guideline-Directed Medical Therapy

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions p...

Active, not recruiting
Ischemic Heart Disease
Coronary Artery Disease
Device: Orbital Atherectomy
Device: Balloon

The aim of the TARGET-IV NA trial is to demonstrate the clinical non-inferiority of the Firehawk® rapamycin eluting stent system in comparison to cur...

Active, not recruiting
Coronary Artery Disease
Device: 2nd generation DES (XIENCE family, Promus family, Resolute/Onyx family/Endeavor, and Orsiro stent)
Device: Microport Firehawk stent

The purpose of this research study is to evaluate whether using the the IMPELLA® CP System temporary circulatory assist device for 30 minutes prior t...

Enrolling
ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Device: Impella CP® placement prior to reperfusion with Primary PCI

The purpose of this study is to test the hypothesis that renal denervation decreases blood pressure and is safe when studied in the presence of up to...

Active, not recruiting
Hypertension
Cardiovascular Diseases
Device: Symplicity Spyral™ multi-electrode renal denervation system
Procedure: Sham Procedure

This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alon...

Enrolling
Pulmonary Embolism
Drug: Anticoagulation Agents
Device: FlowTriever System

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W.L. Gore & Associates logo
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