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Charleston Oncology | Charleston, NC

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Pembrolizumab
Daratumumab
Magrolimab
Capecitabine
Enzalutamide
Bevacizumab
Leucovorin
Sunitinib
AL101
Trastuzumab

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Active trials

12 of 22 total trials

A Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal Cancer (FRESCO-2)

This is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: Placebo
Locations recently updated

This study is being done to see if tucatinib works better than placebo when given with other drugs to treat participants with HER2-positive breast ca...

Active, not recruiting
HER2 Positive Breast Cancer
Drug: Pertuzumab
Drug: Trastuzumab

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will stu...

Active, not recruiting
Diffuse Large B-cell Lymphoma
Drug: Rituximab
Drug: Lenalidomide

The purpose of this study is to evaluate the antitumor effects of sotorasib and RMC-4630 in subjects with KRASG12C mutant NSCLC

Active, not recruiting
Non-Small Cell Lung Cancer
Drug: RMC-4630
Drug: Sotorasib
Locations recently updated

Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tum...

Enrolling
Cancer
Drug: Temozolomide
Drug: Capecitabine

This is a study of pembrolizumab plus gemcitabine/cisplatin versus placebo plus gemcitabine/cisplatin as first-line therapy in participants with adva...

Active, not recruiting
Biliary Tract Carcinoma
Biological: Pembrolizumab
Drug: Placebo

The purpose of this study is to evaluate the safety and efficacy of fixed dose coformulated pembrolizumab/quavonlimab (MK-1308A) plus lenvatinib in a...

Active, not recruiting
Advanced Hepatocellular Carcinoma
Drug: Lenvatinib
Biological: Pembrolizumab

The goals of this clinical study are to learn about the safety, tolerability, dosing and effectiveness of magrolimab in combination with nab-paclitax...

Active, not recruiting
Triple-Negative Breast Cancer
Drug: Sacituzumab Govitecan-hziy
Drug: Magrolimab

The goals of this clinical study are to learn about the safety, tolerability, dosing and effectiveness of magrolimab in combination with docetaxel in...

Active, not recruiting
Solid Tumor
Drug: Docetaxel
Drug: Magrolimab

The primary hypothesis is that pembrolizumab/vibostolimab (MK-7684A) in combination with chemotherapy is superior to pembrolizumab in combination wit...

Active, not recruiting
Metastatic Non-Small Cell Lung Cancer
Biological: Pembrolizumab
Drug: Cisplatin

A Phase 3 Study to Compare AMG 510 with Docetaxel in Non Small Cell Lung Cancer (NSCLC) subjects with KRAS p. G12c mutation

Active, not recruiting
KRAS p, G12c Mutated /Advanced Metastatic NSCLC
Drug: AMG 510
Drug: Docetaxel

The aim of this study is to provide darolutamide treatment to patients who participated in a previous study with darolutamide supported by Bayer and...

Enrolling
Cancer
Drug: Darolutamide (Nubeqa, BAY1841788)

Trial sponsors

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