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Chicago Clinical Research Institute, Inc | Chicago, IL

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Active trials

7 of 33 total trials

A Study of Dotinurad Versus Allopurinol in Participants With Gout

The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol i...

Enrolling
Gout
Drug: Allopurinol
Drug: Dotinurad

The primary objective of this study is to evaluate the efficacy of dotinurad in lowering serum uric acid (sUA) at Week 24 compared with allopurinol i...

Enrolling
Tophaceous Gout
Drug: Allopurinol
Drug: Dotinurad

The main purpose of the proposed study is to evaluate the efficacy of efgartigimod PH20 SC in patients with moderate-to-severe Primary Sjögren's Dise...

Enrolling
Primary Sjogrens Disease
Biological: Efgartigimod PH20 SC
Other: Placebo PH20 SC

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

This study is designed to find out how well the COVID-19 vaccine protects people 50 to 64, who don't have any serious health problems, compared to a...

Enrolling
COVID-19
SARS-COV-2 Infection
Biological: Placebo
Biological: BNT162b2 Vaccine

This is a multicentre, open-label, multiple dose study of INDV-6001 in adult participants with moderate or severe OUD as defined by the Diagnostic an...

Active, not recruiting
Moderate to Severe Opioid Use Disorder
Drug: Suboxone
Drug: INDV-6001

CAPTAIN-T2D will take place in two parts. Part 1 (Screening) will evaluate patients with type 2 diabetes and elevated cortisol risk factors for trial...

Enrolling
Type 2 Diabetes
Cortisol Excess
Drug: clofutriben
Drug: Placebo

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