Children's Hospital Colorado | Pediatric Infectious Disease

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13123 East 16th Avenue, B-055, Aurora, Colorado, United States of America

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Active trials

10 of 40 total trials

A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

This is a nonrandomized study of ruxolitinib in combination with a standard multi-agent chemotherapy regimen for the treatment of B-cell acute lympho...

Active, not recruiting
Drug: Cytarabine
Drug: Leucovorin Calcium

Phase 1 will evaluate the safety and tolerability at different dose levels of repotrectinib in pediatric and young adult subjects with advanced or me...

Locally Advanced Solid Tumors
Primary CNS Tumors
Drug: Oral repotrectinib (TPX-0005)
Locations recently updated

The purpose of this study is to evaluate the efficacy, safety, drug levels, and drug effects of ozanimod in pediatric participants with moderately to...

Crohn Disease
Drug: Ozanimod

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, rec...

Active, not recruiting
Desmoplastic Small Round Cell Tumor
Drug: Ramucirumab
Drug: Cyclophosphamide

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea...

Drug: Ubrogepant

LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation...

Functional Constipation
Irritable Bowel Syndrome With Constipation
Drug: Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 completers)
Drug: Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea...

Drug: Placebo-Matching Ubrogepant
Drug: Ubrogepant

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large...

Ulcerative Colitis
Drug: Upadacitinib

SPIMD-301 is a 48-week, randomized, double-blind, parallel-group, placebo-controlled trial to assess efficacy and safety of single daily subcutaneous...

Active, not recruiting
Mitochondrial Myopathies
Mitochondrial DNA Mutation
Drug: Placebo
Drug: Elamipretide

The aim of this study is to compare the outcomes, ease of use, and cost of the Werewolf FLOW50 device to the institutional standard of care which is...

Anterior Cruciate Ligament Injuries
Arthrofibrosis of Knee
Device: Werewolf FLOW 50
Other: Control

Trial sponsors

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University of Colorado Denver (CU Denver) logo
Bristol-Myers Squibb (BMS) logo
Children's Hospital Colorado logo
Sobi logo
Acadia Pharmaceuticals logo
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Cincinnati Children's Hospital Medical Center logo
Colorado State University (CSU) logo

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