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Chulalongkorn Hospital | Faculty of Medicine, Infectious Disease Unit

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Active trials

17 of 38 total trials

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study (UmbrellaMAX)

The purpose of this extension study is to provide continued treatment with Roche investigational medicinal product (IMP\[s\]) monotherapy or Roche IM...

Enrolling
Cancer
Drug: Entrectinib
Drug: Ipatasertib

The purpose of this study is to assess the efficacy and safety of tiragolumab, an anti-TIGIT monoclonal antibody, when administered in combination wi...

Active, not recruiting
Carcinoma, Hepatocellular
Drug: Tiragolumab
Other: Placebo

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have rec...

Active, not recruiting
Breast Cancer
Drug: Trastuzumab Emtansine
Drug: Placebo

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with end...

Enrolling
Early Breast Cancer
Drug: Endocrine Therapy of Physician's Choice
Drug: Abemaciclib

This is a Phase III, multicenter, randomized, open-label, global study designed to evaluate the efficacy and safety of inavolisib plus fulvestrant co...

Active, not recruiting
Breast Cancer
Drug: Alpelisib
Drug: Inavolisib

This is an open-label, multicenter, non-randomized extension and long-term observational study. Participants receiving atezolizumab monotherapy or at...

Active, not recruiting
Cancer
Drug: Atezolizumab
Drug: Bevacizumab
Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of atezolizumab plus tiragolumab in combination with paclitaxel and cisplatin (PC) c...

Active, not recruiting
Esophageal Cancer
Drug: Tiragolumab Matching Placebo
Drug: Atezolizumab Matching Placebo
Locations recently updated

This is a Phase III, open-label, multicenter, randomized, two-arm study designed to evaluate the efficacy and safety of atezolizumab plus either lenv...

Active, not recruiting
Unresectable Hepatocellular Carcinoma
Drug: Lenvatinib
Drug: Atezolizumab

The purpose of this study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo in participants with unresect...

Active, not recruiting
Esophageal Squamous Cell Carcinoma
Drug: Atezolizumab
Drug: Atezolizumab Matching Placebo

This is a randomized, double-blinded study designed to evaluate the efficacy, safety, pharmacokinetics, and immunogenicity of neoadjuvant treatment w...

Active, not recruiting
Non-Small-Cell Lung
Drug: Cisplatin
Drug: Carboplatin

The purpose of the study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo plus atezolizumab in participa...

Active, not recruiting
Non-Small Cell Lung Cancer
Drug: Tiragolumab
Drug: Atezolizumab

The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of tiragolumab in combination with atezolizumab plus pemetrexed a...

Active, not recruiting
Non-small Cell Lung Cancer (NSCLC)
Drug: Tiragolumab Matching Placebo
Drug: Carboplatin

The study will compare the efficacy and safety of entrectinib with crizotinib in participants with advanced or metastatic ROS1 non-small cell lung ca...

Enrolling
Carcinoma, Non-Small-Cell Lung
Drug: Entrectinib
Drug: Crizotinib

This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, b...

Enrolling
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Diagnostic Test: FoundationOne Liquid CDx Assay (F1LCDx)
Drug: Giredestrant

This is a phase 2/3, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or immuno...

Active, not recruiting
Non-Small Cell Lung Cancer
Drug: Docetaxel
Drug: Entrectinib
Status recently updated

This study is open to adults 40 years or older with idiopathic pulmonary fibrosis (IPF). People can join the study if they are not on any treatment f...

Enrolling
Active, not recruiting
Idiopathic Pulmonary Fibrosis
Drug: Placebo matching BI 1819479
Drug: BI 1819479
Locations recently updated

Adults 40 years of age and older with idiopathic pulmonary fibrosis (IPF) or 18 years and older with progressive pulmonary fibrosis (PPF) can partici...

Enrolling
Progressive Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
Drug: BI 1839100
Drug: Placebo

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