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Clinical Endpoints | Scottsdale, AZ

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SAGE-324
SAR441344
ACP-204
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Frexalimab
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Active trials

12 of 36 total trials

A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD

The goal of this clinical trial is to learn if buntanetap/Posiphen works to treat early Alzheimer's disease in adults aged 55-85. It will also learn...

Enrolling
Early Alzheimers Disease
Drug: buntanetap/posiphen
Drug: Placebo

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disea...

Enrolling
Alzheimer Disease
Drug: Xanomeline Enteric Capsule
Drug: Xanomeline/Trospium Chloride Capsule

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess safety, tolerability, pharmacokinetics, and efficacy of ONO-2020...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: ONO-2020

The purpose of this study is to evaluate the long-term efficacy and safety of combined formulation of xanomeline tartrate/trospium chloride in an imm...

Enrolling
Alzheimer Disease
Agitation
Drug: KarX-EC
Drug: KarXT

This is a master protocol for 3 independent, seamlessly enrolling, multicenter, randomized, double-blind, placebo-controlled, parallel-group studies...

Enrolling
Alzheimer's Disease Psychosis
Drug: Placebo
Drug: ACP-204

This 52-week, open-label extension study is to evaluate the long-term safety and tolerability of ACP-204 in subjects with ADP.

Invitation-only
Alzheimer's Disease Psychosis
Drug: ACP-204
Locations recently updated

The main objectives of the study are to demonstrate pharmacokinetics (PK) similarity between ABP 692 and Ocrelizumab (US), and ABP 692 and Ocrelizuma...

Enrolling
Relapsing-remitting Multiple Sclerosis (RRMS)
Drug: Ocrelizumab (EU)
Drug: Ocrelizumab (US)
Locations recently updated

The purpose of each study is to independently measure the annualized relapse rate (ARR) with administration of frexalimab compared to a daily oral do...

Enrolling
Multiple Sclerosis
Drug: Activated charcoal
Drug: Cholestyramine

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the dis...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: Placebo

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: AR1001
Locations recently updated

This study is to test LHP588 in persons who have mild to moderate Alzheimer's disease (AD) who have shown progressive mental decline in the last year...

Enrolling
Alzheimer Disease
Alzheimer Disease Due to P. Gingivalis
Drug: Placebo Drug
Drug: LHP588

The purpose of this study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants...

Active, not recruiting
Alzheimer Disease, Early Onset
Other: Placebo
Drug: BMS-986446

Trial sponsors

Bristol-Myers Squibb (BMS) logo
Sage Therapeutics logo
AbbVie logo
Acadia Pharmaceuticals logo
Amgen logo
A
Jazz Pharmaceuticals logo
Novo Nordisk logo
Sanofi logo
A

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