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8 of 17
Status: Active
Trial type: Interventional
Funder type: Industry

A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease (VIVID-2)

The reason for this study is to determine the long-term efficacy and safety of the study drug mirikizumab in participants with Crohn's disease.

Crohn's Disease
Drug: Mirikizumab

The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...

Active, not recruiting
Biological: mRNA-1273.222
Biological: mRNA-1283.222

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to...

Biological: Placebo
Biological: Influenza and COVID-19 Combination B

Primary Objective:To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary...

Active, not recruiting
Chronic Obstructive Pulmonary Disease
Drug: Placebo
Drug: Inhaled Long-Acting Muscarinic Antagonist

This study is to understand if the study vaccine (called VLA15) is safe in healthy children.We are looking for children who:are healthyare age 5 thro...

Active, not recruiting
Lyme Disease
Biological: VLA15
Other: Normal Saline

This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary...

Active, not recruiting
Other: Placebo
Biological: SARS-CoV-2 rS/Matrix-M1 Adjuvant (Open Label Crossover Vaccination period)

The study will evaluate the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273.214 severe acute respiratory syndrome coronavirus 2...

Other: Placebo
Biological: mRNA-1273.214

The aim of this 6-month randomized multi-regional double-blind parallel group placebo-controlled phase 3 study is to assess the efficacy and safety o...

Gout Flare
Drug: Placebo
Drug: Tigulixostat

Trial conditions

COVID-19 (3 trials)
Human Influenza (3 trials)
Crohn Disease (2 trials)
Asthma (1 trial)
Chronic Obstructive Pulm... (1 trial)
Gout (1 trial)
Hyperuricemia (1 trial)
Inflammation (1 trial)
Lung Diseases (1 trial)
Lyme Disease (1 trial)

And 4 more

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