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Active trials

15 of 82 total trials

A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 in Healthy Infants

The objective of the study is to evaluate the safety, tolerability, and immunogenicity of 4 injections of VAX-31 (at 4 dose levels) compared to PCV20...

Enrolling
Pneumococcal Vaccines
Biological: 0.5 mL of the mid dose VAX-31
Biological: 0.5 mL of the High-PFS dose VAX-31

The reason for this study is to determine the long-term efficacy and safety of the study drug mirikizumab in participants with Crohn's disease.

Active, not recruiting
Crohn's Disease
Drug: Mirikizumab

This is a Phase 2a/b, randomized, double-blind, placebo-controlled, parallel-group, 6-arm study to evaluate the efficacy and safety of amlitelimab in...

Enrolling
Coeliac Disease
Celiac Disease
Dietary Supplement: SIGE
Drug: Placebo

The purpose of this trial is to assess the safety and relative efficacy of CVXGA (CVXGA50), a KP.2 containing vaccine, compared to COMIRNATY® (COVID-...

Enrolling
COVID-19
Biological: CVXGA (CVXGA50)
Biological: COMIRNATY®

This study aims to check how safe and well-tolerated a second dose of RSVpreF is when given during later pregnancies, and to see how long the immunit...

Enrolling
RSV Infection
Biological: Placebo
Biological: RSVpreF

The purpose of this study is to evaluate how well CD388 works in preventing symptomatic laboratory-confirmed influenza infections, as compared to pla...

Not yet enrolling
Influenza
Combination Product: CD388 Injection
Combination Product: Placebo

This study will evaluate the safety and immunogenicity of the mRNA-1273.214 vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...

Enrolling
SARS-CoV-2
Biological: mRNA-1273.815
Biological: mRNA-1273.214

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prev...

Active, not recruiting
Acute Gastroenteritis
Norovirus Acute Gastroenteritis
Biological: mRNA-1403
Biological: Placebo

BEATRIX (group B strEptococcus mATeRnal and Infant VaX study) The purpose of this study is to learn about the safety and how the group B streptococcu...

Enrolling
Healthy
Biological: Infanrix hexa
Biological: Prevnar 20

The main aim of the study is to assess if TAK-101 can reduce gluten related symptoms and immune activation in adult participants with celiac disease...

Active, not recruiting
Celiac Disease
Drug: TAK-101
Dietary Supplement: Gluten

The purpose of this study is to evaluate the efficacy, immunogenicity and safety of the 9vHPV vaccine in men 20 to 45 years of age. The primary hypot...

Active, not recruiting
Papillomavirus Infections
Biological: 9vHPV Vaccine
Other: Placebo (Saline for Injection)

The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in a...

Begins enrollment in 1 month
Ulcerative Colitis
Drug: LY4268989
Drug: Mirikizumab

The purpose of this study is to evaluate the effectiveness of CD388 in preventing symptomatic laboratory-confirmed influenza infections, as compared...

Active, not recruiting
Influenza
Combination Product: CD388 Injection
Combination Product: Placebo

This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary...

Active, not recruiting
COVID-19
Biological: SARS-CoV-2 rS/Matrix-M1 Adjuvant (Initial Vaccination Period)
Other: Placebo

GLU001 is a first-in-human clinical trial to assess the safety and tolerability of VTP-1000 for adults with celiac disease. This trial will assess VT...

Enrolling
Celiac Disease
Other: Matched Placebo
Biological: VTP-1000

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