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Clinique de l'Europe | Amiens - Pneumology Department

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Pembrolizumab
Pemetrexed
Atezolizumab
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Ribociclib
Osimertinib
Capecitabine
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Active trials

10 of 40 total trials
Locations recently updated

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Researchers want to learn if the study medicines calderasib and subcutaneous (SC) pembrolizumab can be used to treat non-small cell lung cancer (NSCL...

Enrolling
Non-small Cell Lung Cancer
Drug: Carboplatin
Drug: Calderasib

The purpose of this study is to assess the long-term safety and to explore the efficacy of astegolimab in participants with chronic obstructive pulmo...

Enrolling
Chronic Obstructive Pulmonary Disease
Drug: Astegolimab

The advent of CDK4/6 inhibitors (drugs designed to block the action of CDK4/6 proteins, which play a key role in cell proliferation) has improved tre...

Enrolling
Breast Cancer
Other: De-escalation
Drug: Chemotherapy followed by endocrine therapy and ribociclib treatment

Phase 3, randomized, multicentre study to evaluate the efficacy and safety of dostarlimab versus carboplatin-paclitaxel in patients with MMR deficien...

Active, not recruiting
Endometrial Cancer
Drug: Carboplatin-Paclitaxel
Drug: Dostarlimab

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizum...

Enrolling
Solid Tumors
Hematologic Malignancies
Drug: Pembrolizumab
Biological: MK-4280A

TEDOPAM is a randomized (1.1.1) non-comparative phase II study. This study will assess the efficacy and safety of OSE2101 alone or in combination wit...

Active, not recruiting
Metastatic Cancer
Locally Advanced Cancer
Drug: OSE2101
Drug: FOLFIRI

Oxaliplatin ± nivolumab in combination with trifluridine/tipiracil or 5-fluorouracile (5-FU) in frail patients with advanced, recurrent or metastatic...

Enrolling
Esophagus Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: Nivolumab
Drug: FOLFOX regimen

A phase 1/2 open-label multicenter study will be performed with an initial dose escalation part to determine the MTD and/or the RP2D of MCLA-129 in m...

Active, not recruiting
Non-Small Cell Lung Cancer Metastatic
Gastric Cancer
Drug: MCLA-129
Drug: Osimertinib

Study of the combination of luspatercept in low-risk myelodysplastic syndrom (LR-MDS) without ring sideroblasts (RS) having failed or being ineligibl...

Enrolling
MDS
Myelodysplastic Syndromes
Drug: Luspatercept Injection [Reblozyl]
Drug: Eprex

This phase II multicentre randomized open-label study will assess the safety and efficacy of Pembrolizumab in combination with standard chemotherapy...

Active, not recruiting
Inflammatory Breast Cancer
Drug: Pembrolizumab Injection
Drug: neoadjuvant EC-paclitaxel chemotherapy

Trial sponsors

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