Coastal Carolina Research Center | Mount Pleasant, SC

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32 of 71
Status: Active
Trial type: Interventional
Funder type: Industry

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain (CPMP)

The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-s...

Chronic Low-back Pain
Diabetic Neuropathic Pain
Drug: LY3526318 ISA
Drug: LY3857210 ISA
Locations recently updated

a Phase 2 trial to evaluate the blood pressure-lowering effect of lorundrostat (an aldosterone synthase inhibitor), administered on a background of a...

Drug: lorundrostat Dose 2
Drug: lorundrostat Dose 1

This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis...

Lumbar Disc Disease
Biological: BRTX-100
Drug: Saline

The main objective of Part A of this trial is to evaluate the safety and reactogenicity of mRNA-1189 in 18- to 30-year-old healthy adults and the mai...

Active, not recruiting
Epstein-Barr Virus Infection
Biological: mRNA-1189
Biological: Placebo

This Phase 1/2a trial is a randomized, placebo-controlled trial to evaluate the safety, tolerability and immunogenicity of two ascending doses (10^6...

Respiratory Syncytial Virus Infections
Biological: PIV5-vectored RSV Vaccine (BLB-201) Low Dose
Biological: PIV5-vectored RSV Vaccine (BLB-201) High Dose

The purpose of this study is to evaluate the safety, reactogenicity, and relative vaccine efficacy (rVE) of the mRNA-1283.222 vaccine as well as its...

Active, not recruiting
Biological: mRNA-1273.222
Biological: mRNA-1283.222

The purpose of this study is to assess the safety, reactogenicity, and immunogenicity of 3 different doses of ExPEC10V and to select the optimal dose...

Active, not recruiting
Extraintestinal Pathogenic Escherichia Coli Prevention
Biological: ExPEC4V
Biological: Prevnar 13

This is a study of tirzepatide in participants with overweight and obesity. The main purpose is to learn more about how tirzepatide affects body weig...

Active, not recruiting
Drug: Tirzepatide
Drug: Placebo

The purpose of this is study is to compare the efficacy of BHV-3500 (zavegepant) to placebo as a preventive treatment for migraine, as measured by th...

Active, not recruiting
Drug: Placebo
Drug: BHV-3500 (zavegepant)

The main purpose of this study is to evaluate the efficacy of mRNA 1647 vaccine in CMV-seronegative female participants and to evaluate the safety an...

Active, not recruiting
Cytomegalovirus Infection
Biological: mRNA-1647
Biological: Placebo

The mRNA-1273 vaccine is being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) i...

Active, not recruiting
Biological: Placebo
Biological: mRNA-1273

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to...

Biological: Placebo
Biological: Influenza and COVID-19 Combination B

The purpose of this study is to evaluate the safety and immunogenicity of a single intramuscular (IM) injection of different formulations of Quadriva...

Influenza Immunization
Biological: Quadrivalent Influenza mRNA Vaccine MRT5429
Biological: Quadrivalent Influenza mRNA Vaccine MRT5421

The purpose of this study is to assess the change in 24-hour ambulatory blood pressure monitoring (ABPM) between baseline (Day 0) and Day 120 followi...

Drug: Natesto

This study is open to adults who are at least 18 years old and have a body mass index (BMI)bof 27 kg/m2 or more. People can take part if they have ca...

Drug: Placebo
Drug: survodutide

This is a Phase 3 multicenter, double-blind study to evaluate the safety and efficacy of vehicle-controlled topical MOB015B in the treatment of Dista...

Active, not recruiting
Drug: Vehicle (Placebo Comparator)
Drug: MOB015B

A double-blind, randomized, placebo-controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of single injection of...

Active, not recruiting
Drug: RTX-GRT7039
Drug: Placebo

This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the...

Active, not recruiting
Knee Osteoarthritis
Biological: Amniotic Suspension Allograft
Drug: Placebo

This study will be in two parts, Part A and Part B. The primary objective of Part A is to evaluate the contraceptive efficacy of LPRI-CF113. The seco...

Active, not recruiting
Change in Bone Mineral Density
Drug: Drospirenone

The purpose of this study is to test the long-term safety of rimegepant in the acute treatment of moderate or severe migraine in children and adolesc...

Acute Treatment of Migraine
Drug: Rimegepant / BHV3000

Trial conditions

Osteoarthritis (10 trials)
Knee Osteoarthritis (9 trials)
Migraine Disorders (8 trials)
Human Influenza (5 trials)
Obesity (4 trials)
Respiratory Syncytial Vi... (4 trials)
COVID-19 (3 trials)
Overweight (3 trials)
Attention Deficit Disord... (2 trials)
Chikungunya Fever (2 trials)

And 38 more

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