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Coastal Research Institute | Fayetteville, NC

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Top treatments

HU6
Deudomperidone
Survodutide
Cilofexor
Amine
Glecaprevir
Firsocostat
BOS-580
Efimosfermin Alfa
Semicarbazide

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Active trials

6 of 15 total trials
Locations recently updated

A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)

The primary objective of this trial is to evaluate the dose-dependent and comparative effects of ECC4703 (low and high dose), ECC0509 (low and high d...

Enrolling
Metabolic Dysfunction-associated Steatohepatitis
Drug: Placebo
Drug: ECC4703

The purpose of this study is to evaluate the safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of efimosfermin in participants wi...

Enrolling
Metabolic Dysfunction-Associated Steatohepatitis
Drug: Efimosfermin
Drug: Placebo

The participants in this study will have confirmed PBC with inadequate response or intolerance to Ursodeoxycholic acid (UDCA), which is a medication...

Active, not recruiting
Primary Biliary Cholangitis
Other: Placebo
Drug: Elafibranor
Locations recently updated

Rivus Pharmaceuticals. Inc. is sponsoring this research study to assess the safety and tolerability of HU6 as a possible treatment for patients diagn...

Enrolling
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Drug: HU6
Other: Placebo

This study is open to adults who are at least 18 years old and have:* A confirmed liver disease called non-alcoholic steatohepatitis (NASH) or* A con...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis
Combination Product: Survodutide
Combination Product: Placebo matching survodutide

This study is open to adults who are at least 18 years old living with obesity and have:* a confirmed liver disease called non-alcoholic steatohepati...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis (MASH)
Liver Fibrosis
Combination Product: Placebo
Combination Product: Survodutide

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