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Consultants in Neurology, Ltd. | Northbrook, IL

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(Unclaimed)

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Top conditions

Top treatments

Tolebrutinib
SAR442168
Ocrelizumab
AVP-923
Tyrosine
Fampridine
Satralizumab
Ozanimod
Copaxone
Frexalimab

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Active trials

13 of 43 total trials

A Phase 2 Study of Orelabrutinib in Patients With Relapsing-Remitting Multiple Sclerosis

This is a randomized, double-Blind, placebo-controlled Phase 2 Study of Orelabrutinib in Patients with Relapsing-Remitting Multiple Sclerosis.

Active, not recruiting
Relapsing Remitting Multiple Sclerosis
Other: placebo
Drug: orelabrutinib

This is a Phase IIIb, single-arm, multicenter, OLE study. Participants receiving ocrelizumab as an investigational medicinal product (IMP) in a Roche...

Active, not recruiting
Multiple Sclerosis
Drug: Ocrelizumab

The main purpose of this study is to evaluate the safety and efficacy of LY3541860 in adult participants with multiple sclerosis that gets worse and...

Enrolling
Multiple Sclerosis
Drug: LY3541860
Drug: Placebo

The main objective of the study is to evaluate the efficacy of satralizumab compared with placebo based on time from randomization to the first occur...

Enrolling
Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Other: Placebo
Drug: Satralizumab

The purpose of each study is to independently measure the annualized relapse rate (ARR) with administration of frexalimab compared to a daily oral do...

Enrolling
Multiple Sclerosis
Drug: Activated charcoal
Drug: Cholestyramine

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the dis...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: Placebo

The purpose of this study is to collect long-term safety, tolerability, effectiveness and health outcomes data in eligible subjects who have particip...

Enrolling
Relapsing Multiple Sclerosis
Biological: 23-valent pneumococcal polysaccharide vaccine (23-PPV)
Biological: Tetanus toxoid (TT) containing vaccine (Td, Tdap)

Primary Objective:To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMSSecondary Objective:To evalu...

Active, not recruiting
Secondary Progressive Multiple Sclerosis
Drug: Placebo to match Tolebrutinib
Drug: Tolebrutinib

Primary Objective:To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple scler...

Enrolling
Primary Progressive Multiple Sclerosis
Drug: Tolebrutinib
Drug: Placebo

Primary Objective:To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Placebo to match Teriflunomide
Drug: Placebo to match Tolebrutinib

Primary Objective:To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Placebo to match Teriflunomide
Drug: Tolebrutinib

Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients with Progressiv...

Active, not recruiting
Multiple Sclerosis
Drug: Placebo matching IMU-838
Drug: IMU-838

Multi-Center, Randomized, Double-Blinded Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 versus Placebo in Adults with Re...

Enrolling
Multiple Sclerosis
Drug: IMU-838 tablets
Drug: Placebo matching IMU-838 tablets

Trial sponsors

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