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CTI Clinical Research Center | Cincinnati, OH

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AD109
Elinzanetant
LY3305677
JZP258-407
Retatrutide
LY3437943
VEL-101
LY3841136
AVP-786

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Active trials

14 of 18 total trials

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety...

Enrolling
Overweight and Obesity
Obesity
Drug: Placebo
Drug: LY3305677

The main purpose of this study, performed under the master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safet...

Enrolling
Overweight and Obesity
Obesity
Drug: Placebo
Drug: LY3841136

The study is divided into 2 parts: Part 1 and Part 2. The purpose of Part 1 of this study is to generate sufficient safety, reactogenicity, and immun...

Active, not recruiting
Influenza
SARS-CoV-2
Biological: mRNA-1083.3
Biological: Influenza Vaccine 1

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant i...

Enrolling
Prader-Willi Syndrome
Drug: Pitolisant tablet
Other: Placebo tablet

The purpose of this study is to is to evaluate the efficacy and safety of retatrutide in participants with type 2 diabetes in participants who have o...

Enrolling
Overweight
Obesity
Drug: Placebo
Drug: Retatrutide

The purpose of this study is to understand the safety and effects of a combined influenza and COVID-19 vaccine. This combined vaccine is compared to...

Active, not recruiting
COVID-19
Influenza
Biological: COVID-19 Vaccine
Biological: Investigational influenza vaccine

This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic...

Enrolling
Idiopathic Hypersomnia
Narcolepsy
Drug: JZP258 (XYWAV)

Researchers are looking for a better way to treat women who have sleep disturbances associated with menopause.Menopause is part of a natural aging pr...

Enrolling
Sleep Disturbances Associated With Menopause
Other: Placebo
Drug: Elinzanetant

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2...

Enrolling
Agitation in Patients With Dementia of the Alzheimer's Type
Drug: AVP-786

This is a Phase 3 Randomized Double-Blind Placebo-Controlled 1-year Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obs...

Active, not recruiting
OSA
Drug: Placebo
Drug: AD109

This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Ob...

Enrolling
OSA
Drug: Placebo
Drug: AD109

This is an exploratory Phase I, randomized, observer-blind, active-controlled, dose-escalation trial to evaluate four dose levels (DLs) of BNT162b4 g...

Active, not recruiting
COVID-19
SARS-CoV-2 Infection
Biological: BNT162b4 10 µg
Biological: BNT162b4 15 µg
Locations recently updated

A migraine is a moderate to severe headache typically on one side of the head. A migraine attack is a headache that may be accompanied by throbbing,...

Enrolling
Migraine
Drug: Ubrogepant
Drug: Placebo for Ubrogepant

An antibody is a substance your body makes to fight off infection. This study will explore the safety and antibody response of a vaccine to prevent s...

Enrolling
Clostridoides Difficile Associated Disease
Biological: C. difficile vaccine (previously studied formulation).
Biological: C. difficile vaccine formulation 1.

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