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DaVita Clinical Research | Las Vegas, NV

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BI 685509
LNP023
VX-147
KBP-5074
Metformin
SNF472
Inaxaplin
Atrasentan
Bardoxolone Methyl

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Active trials

5 of 13 total trials
Locations recently updated

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

The purpose of this study is to evaluate the long-term safety and tolerability, of open label iptacopan in primary IgA nephropathy participants who h...

Enrolling
Primary IgA Nephropathy
Drug: LNP023

The AFFINITY Study is a phase 2, open-label, basket study to evaluate the efficacy and safety of atrasentan in patients with proteinuric glomerular d...

Active, not recruiting
Immunoglobulin A Nephropathy
Alport Syndrome
Drug: Atrasentan
Locations recently updated

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

The purpose of the study is to evaluate the efficacy, safety, and tolerability of Inaxaplin (IXP) in participants with proteinuric APOL1- mediated ki...

Enrolling
Proteinuric Kidney Disease
Drug: Inaxaplin

The study is designed as a multicenter, randomized, double-blind, placebo controlled study to demonstrate the superiority of iptacopan (LNP023) at a...

Active, not recruiting
IgA Nephropathy
Drug: Placebo
Drug: LNP023

Trial sponsors

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Vertex Pharmaceuticals logo
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