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Active trials

29 of 33 total trials

A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma

This study is trying to find the right dose of a long-lasting medicine called GSK5784283 for people with asthma that remains uncontrolled even though...

Enrolling
Asthma
Drug: GSK5784283
Drug: Placebo

The primary purpose of this study is to evaluate the long-term safety and efficacy of verekitug (UPB-101) in participants who complete the VALIANT st...

Enrolling
Severe Asthma
Drug: Verekitug
Drug: Placebo

The primary objective of this study is to describe the efficacy of rocatinlimab in reducing asthma exacerbations.

Active, not recruiting
Asthma
Drug: Placebo
Drug: Rocatinlimab

The main purpose of the study is to evaluate the efficacy of vixarelimab compared with placebo on lung function in participants with idiopathic pulmo...

Active, not recruiting
Systemic Sclerosis With Lung Involvement
Idiopathic Pulmonary Fibrosis
Drug: Vixarelimab
Drug: Placebo

This study will evaluate the effect of triple ICS/LAMA/LABA therapy with BGF MDI 320/14.4/9.6 μg on cardiopulmonary outcomes relative to LAMA/LABA th...

Enrolling
COPD (Chronic Obstructive Pulmonary Disease)
Drug: BGF MDI 320/14.4/9.6 μg
Drug: GFF MDI 14.4/9.6 μg

A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus pla...

Enrolling
Progressive Pulmonary Fibrosis
Drug: AP01
Other: Placebo

This study will evaluate the efficacy and safety of astegolimab compared with placebo in participants with chronic obstructive pulmonary disease (COP...

Enrolling
Chronic Obstructive Pulmonary Disease (COPD)
Drug: Astegolimab
Drug: Placebo

The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with mod...

Enrolling
Asthma
Drug: Brenipatide
Drug: Placebo

The study is being conducted to evaluate the effect of 3 dosing regimens of povorcitinib on pulmonary function

Enrolling
Moderate to Severe Asthma
Drug: ICS-LABA
Other: placebo

The purpose of this study is to assess the long-term safety and to explore the efficacy of astegolimab in participants with chronic obstructive pulmo...

Enrolling
Chronic Obstructive Pulmonary Disease
Drug: Astegolimab

This Phase IIb dose-ranging study will evaluate the efficacy and safety of 3 different doses of AZD6793 compared with placebo tablets in participants...

Enrolling
Chronic Obstructive Pulmonary Disease (COPD)
Other: Placebo
Drug: AZD6793

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adul...

Enrolling
Chronic Obstructive Pulmonary Disease (COPD)
Biological: Tezepelumab
Other: Placebo

The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will evaluate t...

Active, not recruiting
Severe Asthma
Drug: Placebo
Drug: Verekitug (UPB-101)

This is an open-label extension study for participants who were previously enrolled in and completed an Avalyn Pharma Sponsored study with an inhaled...

Enrolling
Idiopathic Pulmonary Fibrosis (IPF)
Progressive Pulmonary Fibrosis
Combination Product: AP01

This study will evaluate the impact Nintedanib Solution for Inhalation (AP02) has on lung function and key measures of fibrosis in adult patients wit...

Not yet enrolling
Idiopathic Pulmonary Fibrosis (IPF)
Drug: AP02
Drug: Placebo

Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpre...

Enrolling
Asthma
Biological: Depemokimab

This study is researching a drug called dupilumab. The study is focused on patients who have uncontrolled asthma. Asthma is a condition where the air...

Enrolling
Asthma
Drug: dupilumab
Drug: Matching Placebo
Locations recently updated

This is a parallel, Phase 2/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig...

Enrolling
Chronic Obstructive Pulmonary Disease
Drug: Placebo
Drug: Lunsekimig

Study RIN-PF-302 is designed to evaluate the long-term safety and tolerability of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis...

Invitation-only
Progressive Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
Device: Treprostinil Ultrasonic Nebulizer
Drug: Inhaled Treprostinil

The study will evaluate the efficacy and safety of axatilimab in participants with IPF.

Enrolling
Idiopathic Pulmonary Fibrosis
Drug: Axatilimab
Other: Placebo

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