East Kent Hospitals University NHS Foundation Trust | Kent and Canterbury Hospital - Research and Innovation Department

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Ethelbert Road, Canterbury, Kent, England
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6 of 28
Status: Active
Trial type: Interventional
Funder type: Industry

A Study Comparing the Efficacy and Safety of Polatuzumab Vedotin With Rituximab-Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab-Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Diffuse Large B-Cell Lymphoma (POLARIX)

This Phase III, randomized, double-blind, placebo-controlled study will compare the efficacy, safety, and pharmacokinetics of polatuzumab vedotin plu...

Active, not recruiting
Diffuse Large B-Cell Lymphoma
Drug: Polatuzumab vedotin Placebo
Drug: Vincristine Placebo

To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Rituximab
Drug: Venetoclax

The purpose of this study is to compare the efficacy and safety of glofitamab in combination with polatuzumab vedotin plus rituximab, cyclophosphamid...

Large B-Cell Lymphoma
Drug: Polatuzumab vedotin
Drug: Rituximab

COVID-19 (SARS-CoV2 virus) was declared a global pandemic by the WHO on 11th March 2020. Currently there are no drugs proven to prevent COVID-19 or t...

Drug: Sotrovimab
Drug: Placebo

Waldenström's macroglobulinaemia (WM) is a rare type of slow growing lymphoma. It develops when white blood cells grow abnormally.Typically a disease...

Waldenstrom Macroglobulinemia
Drug: Dexamethasone, cyclophosphamide, rituximab
Drug: Rituximab, ibrutinib

Follicular Lymphoma (FL) is the second most common B-cell cancer and the most common type of cancer of lymphocytes. Unfortunately, this disease is in...

Follicular Lymphoma (FL)
Drug: Rituximab
Drug: Lenalidomide

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