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KarXT
ITI-1284
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Active trials

6 of 7 total trials

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-2)

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC in adult participants with agitation related to Alzheimer's Disea...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: Xanomeline Enteric Capsule

This is a Phase 3, 38-week, randomized, double-blind, placebo-controlled, multicenter, outpatient study in subjects with psychosis associated with Al...

Enrolling
Psychosis Associated With Alzheimer's Disease
Drug: Placebo
Drug: KarXT

This is a multicenter, randomized, double-blind, placebo-controlled, flexible-dose study of the efficacy, safety, and tolerability of ITI-1284 in pat...

Enrolling
Agitation Associated With Alzheimer's Dementia
Drug: Placebo
Drug: ITI-1284

This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerab...

Enrolling
Psychosis Associated With Alzheimer's Disease
Drug: Placebo
Drug: ITI-1284

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease (AD) with mod...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

This is a Phase 3 global, multicenter, 52-week, open-label extension (OLE) rollover study for subjects completing study CN012-0026, CN012-0027 or CN0...

Enrolling
Psychosis Associated With Alzheimer's Disease
Drug: KarXT

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Bristol-Myers Squibb (BMS) logo
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