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SEP-363856
KarXT
Rapastinel
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Azetukalner
Brenipatide
Aripiprazole
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Active trials

21 of 130 total trials

52-week Open Label Safety-Tolerability Study (NOVA3)

Phase 3, open label, multicenter study designed to assess the long term safety and tolerability of LB-102 for the treatment of adult patients with st...

Enrolling
Schizophrenia
Drug: LB-102

This is a Phase 4, randomized, blinded, active-controlled, multicohort study to evaluate HTX-011 compared with bupivacaine HCl in subjects undergoing...

Active, not recruiting
Analgesia
Drug: HTX-011
Drug: Acetaminophen

X-CEED is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of azetukalner in adult part...

Active, not recruiting
Bipolar II Disorder
Bipolar I Disorder
Drug: Placebo
Drug: Azetukalner

X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of...

Active, not recruiting
Major Depressive Disorder
Drug: Placebo
Drug: Azetukalner

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and...

Enrolling
Alcohol Use Disorder
Drug: Placebo
Drug: LY3537031

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use...

Enrolling
Alcohol Use Disorder
Drug: LY3537031
Drug: Placebo

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when u...

Enrolling
Opioid Use Disorder
Drug: Brenipatide
Drug: Buprenorphine

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of etavopivat and test how well etavopivat works compared to plac...

Active, not recruiting
Sickle Cell Disease
Drug: Placebo Tablets
Drug: Etavopivat Tablets High dose

Schizophrenia is a common and severe psychiatric illness characterized by extreme disturbances of cognition and thought, affecting language, percepti...

Enrolling
Schizophrenia
Drug: Placebo
Drug: Emraclidine

Major depressive disorder (MDD; depression) is a mood disorder that causes a continued feeling of sadness and loss of interest. It is a common and se...

Enrolling
Major Depressive Disorder
Drug: Icalcaprant
Drug: Placebo for Icalcaprant

This is a phase 3, open-label extension study to assess the long-term safety of KarXT for the treatment of mania or mania with mixed features in Bipo...

Enrolling
Bipolar Disorder Type I With Mania
Drug: Valproate
Drug: Lamotrigine
Locations recently updated

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder

Enrolling
Bipolar-I Disorder With Mania or Mania With Mixed Features
Drug: KarXT
Other: Placebo

This study aims to find out whether a study medicine called survodutide helps people control their blood sugar. Adults who live with type 2 diabetes...

Enrolling
Type 2 Diabetes
Drug: Survodutide
Drug: Placebo

Evaluate the efficacy and safety of Ulotaront (SEP-363856) in acutely psychotic subjects with schizophrenia

Active, not recruiting
Schizophrenia
Drug: SEP-363856
Other: Placebo

X-CEED-OLE is a Phase 3, multicenter, open-label study to evaluate the long-term safety, tolerability, and efficacy of azetukalner in adult participa...

Active, not recruiting
Bipolar II Disorder
Bipolar I Disorder
Drug: Azetukalner

X-NOVA-OLE is a multicenter, open-label study to evaluate the long-term safety, tolerability, and efficacy of azetukalner as a monotherapy in adult p...

Active, not recruiting
Major Depressive Disorder
Drug: Azetukalner

This study is a randomized, double-blind, placebo and active-controlled, multicenter trial conducted to evaluate whether PP-01 mitigates the withdraw...

Enrolling
Cannabis Withdrawal
Combination Product: PP-01
Drug: Nabilone

Open label extension, long-term multicenter study of safety and efficacy of SPN-812 in pediatric ADHD patients

Active, not recruiting
Attention-Deficit/Hyperactivity Disorder
Drug: SPN-812

This is a clinical research study for an investigational drug called RAP-219 in participants with bipolar I disorder. This study is being conducted t...

Active, not recruiting
Bipolar 1 Disorder
Drug: RAP-219
Other: Placebo

This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy...

Enrolling
Generalized Anxiety Disorder
Drug: Placebo
Drug: ITI-1284 10 mg

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