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Eye Research Foundation | Newport Beach, CA

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Bimatoprost
Latanoprost
AR-15512
AMDX-2011P
AGN-195263
Pilocarpine HCl
RVL-1201
Timolol
KPI-121
PF-04217329

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Active trials

19 of 105 total trials

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease (PREDICT-1)

The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to ve...

Enrolling
Dry Eye Disease (DED)
Other: Vehicle of licaminlimab
Other: Artificial Tear Run-in

Dry Eye Disease (DED) refers to a long-term condition that happens when there is not enough lubrication in your eyes. This can happen when your eye c...

Active, not recruiting
Dry Eye Disease
Drug: ABBV-444
Drug: REFRESH OPTIVE UD

The objective is to evaluate the safety and efficacy of low dose and high dose CBT-001 eye drop dosed twice daily for 24 months compared to vehicle i...

Active, not recruiting
Pterygium
Drug: CBT-001
Drug: Vehicle

This study is to establish non-inferiority of a preservative free formulation of Bimatoprost ophthalmic solution 0.01% (YSBP) of YS Life Science Co.,...

Enrolling
Ocular Hypertension (OH)
Primary Open Angle Glaucoma (POAG)
Drug: Bimatoprost ophthalmic solution 0.01% YSBP
Drug: bimatoprost ophthalmic solution 0.01% (Lumigan®)

This study is a multicenter, double-masked, vehicle-controlled, randomized, parallel group study designed to evaluate the treatment of abnormal meibo...

Active, not recruiting
Dry Eye Disease
Other: Vehicle
Drug: AZR-MD-001

A randomized, double-blind, parallel-group, two-arm, multiple dose, multicenter, clinical endpoint bioequivalence study

Enrolling
Open-angle Glaucoma
Ocular Hypertension
Drug: LUMIGAN® (bimatoprost ophthalmic solution) 0.01%
Drug: Bimatoprost Ophthalmic Solution, 0.01%

The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P...

Enrolling
Alzheimer Disease
Drug: AMDX-2011P

The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P...

Enrolling
Cerebral Amyloid Angiopathy
Drug: AMDX-2011P

The purpose of this research study is to assess the ability of AMDX- 2011P to identify amyloid deposits in the retina of participants with Primary Op...

Enrolling
Primary Open Angle Glaucoma
Drug: AMDX-2011P

The purpose of this study is to assess the effectiveness and safety of a single dose of Corabotase (also known as IPN10200) compared to placebo (doub...

Enrolling
Moderate to Severe Glabellar Lines
Biological: Corabotase
Biological: Placebo

This study is open to adults aged 50 years and older with geographic atrophy that was diagnosed by imaging of the retina. The purpose of this study i...

Active, not recruiting
Geographic Atrophy
Drug: BI 1584862
Drug: Placebo-matching BI 1584862

This study is open to adults 18 and older with an eye condition called diabetic macular edema. People are required to have a specific type of diabeti...

Enrolling
Macular Edema
Drug: BI 1815368
Drug: Placebo

This study is open to people 50 years or older with an eye condition called geographic atrophy. The purpose of this study is to compare a medicine ca...

Active, not recruiting
Macular Degeneration, Age-related
Geographic Atrophy
Drug: Pegcetacoplan
Drug: Sham comparator to BI 771716

This is a Phase 2, randomized, multicenter, double masked, vehicle controlled, parallel group study to evaluate the efficacy and safety of DFL24498 t...

Enrolling
Dry Eye Disease (DED)
Other: Vehicle
Drug: DFL24498

This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonst...

Enrolling
Ocular Hypertension
Glaucoma, Open-Angle
Drug: Test - Bimatoprost 0.01% Ophthalmic Solution
Drug: Reference - LUMIGAN® (Bimatoprost 0.01% Ophthalmic Solution)

The goal of this clinical trial is to determine the dose of PA5108 Ocular Implant that is effective and safe for the reduction of intraocular pressur...

Active, not recruiting
Ocular Hypertension
Glaucoma, Open-Angle
Combination Product: PA5108 Ocular Implant low dose
Drug: Latanoprost 0.005% Ophthalmic Solution

The goal of this clinical trial is to learn if Phentolamine Ophthalmic Solution works to treat adults that have had keratorefractive surgery and have...

Active, not recruiting
Vision Loss Night
Vision Disorders
Drug: 0.75% Phentolamine Ophthalmic Solution
Drug: Placebo

The primary purpose of this study is to evaluate the safety and durability of single- and repeat administration of AR-14034 Sustained Release (SR) in...

Active, not recruiting
Neovascular Age-related Macular Degeneration (nAMD)
Drug: AR-14034 SR implant lower dose
Drug: Sham procedure

Neovascular age-related macular degeneration (nAMD), also known as "wet" AMD, is the abnormal growth of new blood vessels in the light-sensitive tiss...

Enrolling
Neovascular Age-related Macular Degeneration
Drug: Surabgene Lomparvovec (ABBV-RGX-314)
Drug: Ranibizumab Control

Trial sponsors

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