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Eye Research Foundation | Newport Beach, CA

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Top conditions

Top treatments

Bimatoprost
Latanoprost
AR-15512
AMDX-2011P
Pilocarpine HCl
AGN-195263
DE-117
KPI-121
MT10109L
K-161

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Active trials

14 of 80 total trials

A Phase 3 Study to Evaluate AZR-MD-001 in Patients with Abnormal Meibomian Gland Function and Dry Eye Disease (DED)

This study is a multicenter, double-masked, vehicle-controlled, randomized, parallel group study designed to evaluate the treatment of abnormal meibo...

Active, not recruiting
Dry Eye Disease
Other: Vehicle
Drug: AZR-MD-001

A randomized, double-blind, parallel-group, two-arm, multiple dose, multicenter, clinical endpoint bioequivalence study

Enrolling
Open-angle Glaucoma
Ocular Hypertension
Drug: LUMIGAN® (bimatoprost ophthalmic solution) 0.01%
Drug: Bimatoprost Ophthalmic Solution, 0.01%

The purpose of this study is to evaluate tear production following acute administration of AR-15512 ophthalmic solution 0.003% (0.003% AR-15512) in s...

Enrolling
Dry Eye Disease
Drug: 0.003% AR-15512

The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P...

Enrolling
Alzheimer Disease
Drug: AMDX-2011P

The purpose of this study is to assess safety, tolerability, plasma pharmacokinetics and biologic activity of a single intravenous dose of AMDX-2011P...

Enrolling
Cerebral Amyloid Angiopathy
Drug: AMDX-2011P

The purpose of this research study is to assess the ability of AMDX- 2011P to identify amyloid deposits in the retina of participants with Primary Op...

Enrolling
Primary Open Angle Glaucoma
Drug: AMDX-2011P

The purpose of this research study is to assess safety and tolerability of a single intravenous (given through a vein) dose of the investigational re...

Enrolling
Parkinson Disease
Amyotrophic Lateral Sclerosis
Drug: AMDX2011P

The purpose of this study is to assess the safety and efficacy of FID 123320 Ophthalmic Solution compared to Vehicle for relieving redness of the eye...

Enrolling
Ocular Redness
Eye Irritation
Drug: FID 123320 Ophthalmic Solution
Drug: Vehicle

This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonst...

Enrolling
Ocular Hypertension
Glaucoma, Open-Angle
Drug: Test - Bimatoprost 0.01% Ophthalmic Solution
Drug: Reference - LUMIGAN® (Bimatoprost 0.01% Ophthalmic Solution)

The main purpose is to compare the ocular hypotensive efficacy and safety of two concentrations of T4090 (Kinezodianone R HCl 0.2% and 0.3%) ophthalm...

Active, not recruiting
Glaucoma
Ocular Hypertension
Drug: Rhopressa®
Drug: T4090 0.3%

The purpose of this study is to evaluate reflex tear production following cotton swab nasal stimulation in subjects with dry eye disease (DED).

Enrolling
Dry Eye Disease
Procedure: Cotton Swab Nasal Stimulation

The objective of this clinical study is to evaluate the safety and efficacy of NCX 470 Ophthalmic Solution in lowering intraocular pressure (IOP) in...

Enrolling
Open Angle Glaucoma
Ocular Hypertension
Drug: Latanoprost 0.005%
Drug: NCX 470 0.1%

The purpose of this two-stage clinical trial is to assess the safety and hypotensive efficacy of AR-17043 and PG043 ophthalmic solutions in subjects...

Enrolling
Open Angle Glaucoma
Ocular Hypertension
Drug: AR-17043 Ophthalmic Solution
Drug: Netarsudil 0.02%/Latanoprost 0.005% Ophthalmic Solution

To demonstrate the safety and effectiveness of TearCare® procedures compared to Restasis® to treat the signs and symptoms of dry eye disease in adult...

Active, not recruiting
Dry Eye
Meibomian Gland Dysfunction
Device: TearCare System
Drug: Restasis

Trial sponsors

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