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Frenova Renal Research | Houston Medical Research Institute, LLC

Research site
(Unclaimed)

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Top conditions

Top treatments

Povetacicept
VX-147
Clazakizumab

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Active trials

3 of 3 total trials

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study. Part 1 (phase 2b) is a do...

Enrolling
Atherosclerotic Cardiovascular Disease
Atherosclerotic Cardiovascular Disease in Patients With ESKD
Drug: Placebo
Drug: CSL300

The purpose of this study is to evaluate the efficacy of povetacicept in adult participants compared with placebo in reducing proteinuria and preserv...

Active, not recruiting
Immunoglobulin A Nephropathy
Drug: Placebo (matched to Povetacicept)
Drug: Povetacicept

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Trial sponsors

CSL Behring logo
Vertex Pharmaceuticals logo
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