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Active trials

9 of 87 total trials

A Phase 1 Study to Evaluate JCXH-108, an MRNA-based Vaccine Against RSV

The goal of this clinical trial is to assess the safety, reactogenicity and immunogenicity of an mRNA-based vaccine, JCXH-108, the prevention of Resp...

Enrolling
Respiratory Syncytial Virus (RSV)
Infectious Disease
Other: Placebo
Biological: JCXH-108

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1010, and to evaluate relative vaccine efficacy (rVE) of m...

Enrolling
Seasonal Influenza
Biological: Fluarix®
Biological: Influsplit®

The purpose of this study (Part 1 and Part 2) is to evaluate the relative vaccine efficacy (rVE), safety, reactogenicity, and immunogenicity of mRNA-...

Active, not recruiting
COVID-19
Biological: mRNA-1283.222
Biological: mRNA-1273.815

The primary objectives of this study are to evaluate the safety and reactogenicity of mRNA-1403, and to demonstrate the efficacy of mRNA-1403 to prev...

Enrolling
Acute Gastroenteritis
Norovirus Acute Gastroenteritis
Biological: mRNA-1403
Biological: Placebo

This study is open to adults who are at least 18 years old and have* presumed or confirmed NASH together with overweight or obesity and* a body mass...

Enrolling
Non-Alcoholic SteatoHepatitis (NASH)
Obesity
Drug: Survodutide
Drug: Placebo

The goal of this clinical trial is to assess the clinical response to a drug combination type of polypill in patients with AD after 180 days of treat...

Enrolling
Alzheimer Disease
Drug: MAR

The purpose of this study is to select a dose of CD388 that is effective in preventing symptomatic laboratory-confirmed influenza infections, as comp...

Active, not recruiting
Influenza
Combination Product: CD388 Injection
Combination Product: Placebo

The goal of this clinical study is to learn more about the study drug, obeldesivir (ODV; GS-5245), and how safe and effective it is in treating nonho...

Enrolling
RSV Infection
Drug: Obeldesivir
Drug: Obeldesivir Placebo

This is a Phase 3, randomized, parallel-group, comparator-controlled, observer-blind, multicenter study of immunogenicity and safety in approximately...

Active, not recruiting
Influenza, Human
Biological: licensed QIV2
Biological: Investigational aQIVc

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